Talk:Bat flight
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==Wiki Education assignment: Comparative Anatomy== This article was the subject of a Wiki Education Foundation-supported course assignment, between 7 February 2022 and 20 May 2022. Further details are available on the course page. Student editor(s): Ramen Scientist, DuneBuggy123, Scientist06 (article contribs). Peer reviewers: Azyla.m.
Evolution
The expansion of the long bones in bat wings is at at least partly attributed to paired-box (PAX) homeodomain transcription factor, Prx1. It is believed that changes in the Prx1 enhancer along with other molecular factors lead to the morphological separation of bats from their ancestors.[1] Up-regulation of the bone morphogenetic protein (BMP) signaling pathway is also crucial in developmental and evolutionary elongation of bat forelimb digits.[2] Fgf10 signaling is also likely required for the development of bat wing membrane and muscles.[3]
Cooper, Kimberly L.; Tabin, Clifford J. (2008-01-15). "Understanding of bat wing evolution takes flight". Genes & Development. 22 (2): 121–124. doi:10.1101/gad.1639108. ISSN 0890-9369. PMC 2731632. PMID 18198331. Sears, Karen E.; Behringer, Richard R.; Rasweiler, John J.; Niswander, Lee A. (2006-04-25). "Development of bat flight: Morphologic and molecular evolution of bat wing digits". Proceedings of the National Academy of Sciences. 103 (17): 6581–6586. doi:10.1073/pnas.0509716103. ISSN 0027-8424. PMC 1458926. PMID 16618938.Scientist06 (talk) 21:07, 10 May 2022 (UTC) Tokita, Masayoshi; Abe, Takaaki; Suzuki, Kazuo (2012-12-18). "The developmental basis of bat wing muscle". Nature Communications. 3 (1): 1302. doi:10.1038/ncomms2298. ISSN 2041-1723. — Preceding unsigned comment added by Scientist06 (talk • contribs) 21:05, 10 May 2022 (UTC)
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