Talk:SMIM19

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	This article was accepted from this draft on 22 April 2022 by reviewer DGG (talk · contribs).

Untitled

From draft page:

*I think it needs to be reconsidered if this is OR -- and if there are possibly further references  DGG ( talk ) 07:59, 14 October 2021 (UTC)[reply]

A lot of this draft is very useful. The main problem is it's hard to tell which aspects are original reserach and which not. Also, within the original reserach, soe is non-controversial (e.g. summarising established transcript variants from NCBI) whereas some is more highly speculative and would require detailed methods sections if submitted to a research journal. The first aspects that come to mind are:A) the upstreeam sequence structural prediction using ITASSER - accurate de novo prediciont is a notoriously difficult task and you can't just stick any sequence in ITASSER or SWISSMODEL and trust any output, so way more detail would be needed on steps taken, accurracy adsessments etc. B) The phylogeny in File:Phylogenetic_tree.png, is it neighbour joiining, Max likelihood, Bayesian; on what portionas of teh sequenecs; using what substitutiona model; amino acid or nucleotide; how many bootstraps etc.
To summarise: Either the original research needs to be stripped out or referencded to a research paper that estabilishes that it's been accurately and robustly done. T.Shafee(Evo&Evo)^talk 07:44, 16 April 2021 (UTC)[reply]