Talk:Systemic lupus erythematosus

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Ethnic frequencies[edit]

http://www.lupusny.org/about-lupus/who-gets-lupus

African-American women are three times more likely than Caucasian women to get lupus and develop severe symptoms, with as many as 1 in every 250 affected.

And the disease is two times more prevalent in Asian-American and Latina women than it is in Caucasian women. Women of Native American descent are also disproportionately affected.

The famous Lupus in Minorities: Nature Versus Nurture (LUMINA) study—a large multi-ethnic, multi-regional, and multi-institutional examination of lupus begun in 1993—found that genetic and ethnic factors are more important than socioeconomic ones in influencing disease activity. — Preceding unsigned comment added by Nbauman (talkcontribs) 23:04, 24 August 2015 (UTC)

Treatment: cyclophosphamide[edit]

Because of potential side-effects, cyclophosphamide (CYC) is used in early phases of treatment for severe cases and substituted with other medications for maintenance therapy.[1]

References

  1. ^ Davis, LS; Reimold, AM (1 April 2017). "Research and therapeutics-traditional and emerging therapies in systemic lupus erythematosus". Rheumatology (Oxford, England). 56 (suppl_1): i100–i113. doi:10.1093/rheumatology/kew417. PMID 28375452.

— Preceding unsigned comment added by Winelibrarian (talkcontribs) 15:55, 17 January 2019 (UTC)

Treatment option clarification[edit]

Treatment option clarification: following "There is no cure for SLE.[1] Treatments may include NSAIDs, corticosteroids, immunosuppressants, hydroxychloroquine, and methotrexate.[1]"

insert: Corticosteroids is one of the most effective therapies resulting in immediate mitigation of inflammation. Long term use of corticosteroids results in significant side-effects. [1] --Swozingram (talk) 23:03, 19 September 2019 (UTC)

Okay ref says "CSs are one of the most effective therapies for immediately dampening inflammation; however, long-term use of CSs can cause serious side-effects"
Will add but paraphrase more.

Doc James (talk · contribs · email) 00:17, 20 September 2019 (UTC)