Thomas Osborne

Thomas Osborne may refer to:

• Thomas Osborne, 1st Duke of Leeds (1632–1712), English Lord High Treasurer, Lord President of the Council and MP for York
• Sir Thomas Osborne, 5th Baronet (1639–1715), Irish baronet and landowner
• Thomas Osborne (publisher) (1704?–1767), English publisher and bookseller
• Thomas Osborne, 4th Duke of Leeds (1713–1789), British Justice in Eyre and Cofferer of the Household
• Sir Thomas Osborne, 9th Baronet (1757–1821), Irish baronet and politician
• Thomas Burr Osborne (politician) (1798–1869), U.S. Representative from Connecticut
• Thomas Osborne (Australian journalist) (c. 1806–1853), Australian journalist and politician in the Victorian Legislative Council
• Thomas W. Osborn (1833–1898), U.S. Senator from Florida
• Thomas O. Osborn (1832–1904), American lawyer, soldier, and diplomat
• Thomas A. Osborn (1836–1898), Governor of Kansas
• Thomas Mott Osborne (1859–1926), American prison reformer
• Thomas Burr Osborne (chemist) (1859–1929), chemist, co-discoverer of Vitamin A
• Tom Osborne (born 1937), US college football head coach and member of Congress
• Tom Osborne (Canadian politician) (born 1964), Newfoundland and Labrador politician