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Thujopsene synthase

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Thujopsene synthase
Identifiers
EC no.4.2.3.79
Databases
IntEnzIntEnz view
BRENDABRENDA entry
ExPASyNiceZyme view
KEGGKEGG entry
MetaCycmetabolic pathway
PRIAMprofile
PDB structuresRCSB PDB PDBe PDBsum
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PMCarticles
PubMedarticles
NCBIproteins

Thujopsene synthase (EC 4.2.3.79) is an enzyme with systematic name (2E,6E)-farnesyl diphosphate lyase (cyclizing, (+)-thujopsene-forming).[1][2] This enzyme catalyses the following chemical reaction

(2E,6E)-farnesyl diphosphate (+)-thujopsene + diphosphate

The recombinant enzyme from the plant Arabidopsis thaliana produces (+)-alpha-barbatene, (+)-thujopsene and (+)-beta-chamigrene.

References

  1. ^ Wu, S.; Schoenbeck, M.A.; Greenhagen, B.T.; Takahashi, S.; Lee, S.; Coates, R.M.; Chappell, J. (2005). "Surrogate splicing for functional analysis of sesquiterpene synthase genes". Plant Physiol. 138: 1322–1333. doi:10.1104/pp.105.059386. PMC 1176406. PMID 15965019.
  2. ^ Tholl, D.; Chen, F.; Petri, J.; Gershenzon, J.; Pichersky, E. (2005). "Two sesquiterpene synthases are responsible for the complex mixture of sesquiterpenes emitted from Arabidopsis flowers". Plant J. 42: 757–771. doi:10.1111/j.1365-313x.2005.02417.x. PMID 15918888.

External links