UBOX5

UBOX5
Identifiers
Aliases	UBOX5, RNF37, UBCE7IP5, UIP5, hUIP5, U-box domain containing 5
External IDs	MGI: 2154658; HomoloGene: 8972; GeneCards: UBOX5; OMA:UBOX5 - orthologs
Gene location (Human)
Chr.	Chromosome 20 (human)
End	3,160,196 bp
Gene location (Mouse)
Chr.	Chromosome 2 (mouse)
End	130,471,958 bp
RNA expression pattern
	Top expressed in
	gonad; ; parotid gland; ; gastrocnemius muscle; ; muscle of thigh; ; skeletal muscle tissue; ; blood; ; Region I of hippocampus proper; ; popliteal artery; ; tibial arteries; ; inferior olivary nucleus;
	Top expressed in
	otic vesicle; ; otic placode; ; spermatocyte; ; zygote; ; genital tubercle; ; female urethra; ; tail of embryo; ; maxillary prominence; ; mandibular prominence; ; saccule;
	More reference expression data
	n/a
Gene ontology
Molecular function	ubiquitin-ubiquitin ligase activity; protein binding; ubiquitin protein ligase binding; metal ion binding; ubiquitin protein ligase activity; ubiquitin-protein transferase activity; transferase activity;
Cellular component	nuclear body; nucleus; nucleoplasm; focal adhesion;
Biological process	protein polyubiquitination; protein ubiquitination;
	Sources:Amigo / QuickGO
Orthologs
	22888
	140629
	ENSG00000185019
	ENSMUSG00000027300
	O94941
	Q925F4
	NM_199415; NM_001267584; NM_014948
	NM_001255993; NM_001255994; NM_080562
	NP_001254513; NP_055763; NP_955447
	NP_001242922; NP_001242923; NP_542129
	Wikidata
View/Edit Human	View/Edit Mouse

RING finger protein 37 is a protein that in humans is encoded by the UBOX5 gene.^[5]^[6]

Interactions

UBOX5 has been shown to interact with UBE2L3.^[5]

References

^ ^a ^b ^c GRCh38: Ensembl release 89: ENSG00000185019 – Ensembl, May 2017
^ ^a ^b ^c GRCm38: Ensembl release 89: ENSMUSG00000027300 – Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ ^a ^b Pringa E, Martinez-Noel G, Muller U, Harbers K (May 2001). "Interaction of the ring finger-related U-box motif of a nuclear dot protein with ubiquitin-conjugating enzymes". J Biol Chem. 276 (22): 19617–23. doi:10.1074/jbc.M100192200. PMID 11274149.{{cite journal}}: CS1 maint: unflagged free DOI (link)
^ "Entrez Gene: UBOX5 U-box domain containing 5".

Maruyama K, Sugano S (1994). "Oligo-capping: a simple method to replace the cap structure of eukaryotic mRNAs with oligoribonucleotides". Gene. 138 (1–2): 171–4. doi:10.1016/0378-1119(94)90802-8. PMID 8125298.
Suzuki Y, Yoshitomo-Nakagawa K, Maruyama K, Suyama A, Sugano S (1997). "Construction and characterization of a full length-enriched and a 5'-end-enriched cDNA library". Gene. 200 (1–2): 149–56. doi:10.1016/S0378-1119(97)00411-3. PMID 9373149.
Nagase T, Ishikawa K, Suyama M, Kikuno R, Hirosawa M, Miyajima N, Tanaka A, Kotani H, Nomura N, Ohara O (1999). "Prediction of the coding sequences of unidentified human genes. XII. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro". DNA Res. 5 (6): 355–64. doi:10.1093/dnares/5.6.355. PMID 10048485.
Martinez-Noel G, Niedenthal R, Tamura T, Harbers K (1999). "A family of structurally related RING finger proteins interacts specifically with the ubiquitin-conjugating enzyme UbcM4". FEBS Lett. 454 (3): 257–61. doi:10.1016/S0014-5793(99)00823-6. PMID 10431818.
Rual JF, Venkatesan K, Hao T, Hirozane-Kishikawa T, Dricot A, Li N, Berriz GF, Gibbons FD, Dreze M, Ayivi-Guedehoussou N, Klitgord N, Simon C, Boxem M, Milstein S, Rosenberg J, Goldberg DS, Zhang LV, Wong SL, Franklin G, Li S, Albala JS, Lim J, Fraughton C, Llamosas E, Cevik S, Bex C, Lamesch P, Sikorski RS, Vandenhaute J, Zoghbi HY, Smolyar A, Bosak S, Sequerra R, Doucette-Stamm L, Cusick ME, Hill DE, Roth FP, Vidal M (2005). "Towards a proteome-scale map of the human protein-protein interaction network". Nature. 437 (7062): 1173–8. doi:10.1038/nature04209. PMID 16189514.

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[refGRCh38Ensembl-1] GRCh38: Ensembl release 89: ENSG00000185019 – Ensembl, May 2017

[refGRCm38Ensembl-2] GRCm38: Ensembl release 89: ENSMUSG00000027300 – Ensembl, May 2017

[3] "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[4] "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[pmid11274149-5] Pringa E, Martinez-Noel G, Muller U, Harbers K (May 2001). "Interaction of the ring finger-related U-box motif of a nuclear dot protein with ubiquitin-conjugating enzymes". J Biol Chem. 276 (22): 19617–23. doi:10.1074/jbc.M100192200. PMID 11274149.{{cite journal}}: CS1 maint: unflagged free DOI (link)

[entrez-6] "Entrez Gene: UBOX5 U-box domain containing 5".

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Interactions

References

Further reading