UDP-glucose 4,6-dehydratase
| UDP-glucose 4,6-dehydratase | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifiers | |||||||||
| EC no. | 4.2.1.76 | ||||||||
| CAS no. | 68189-53-7 | ||||||||
| Databases | |||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB structures | RCSB PDB PDBe PDBsum | ||||||||
| Gene Ontology | AmiGO / QuickGO | ||||||||
| |||||||||
In enzymology, an UDP-glucose 4,6-dehydratase (EC 4.2.1.76) is an enzyme that catalyzes the chemical reaction
- UDP-glucose UDP-4-dehydro-6-deoxy-D-glucose + H2O
Hence, this enzyme has one substrate, UDP-glucose, and two products, UDP-4-dehydro-6-deoxy-D-glucose and H2O.
This enzyme belongs to the family of lyases, specifically the hydro-lyases, which cleave carbon-oxygen bonds. The systematic name of this enzyme class is UDP-glucose 4,6-hydro-lyase (UDP-4-dehydro-6-deoxy-D-glucose-forming). Other names in common use include UDP-D-glucose-4,6-hydrolyase, UDP-D-glucose oxidoreductase, and UDP-glucose 4,6-hydro-lyase. This enzyme participates in nucleotide sugars metabolism.
References
- Kamsteeg J, Van Brederode J, Van Nigtevecht G (1978). "The formation of UDP-L-rhamnose from UDP-D-glucose by an enzyme preparation of red campion (Silene dioica (L) Clairv) leaves". FEBS Lett. 91 (2): 281–4. doi:10.1016/0014-5793(78)81192-2. PMID 680134.
{{cite journal}}: CS1 maint: multiple names: authors list (link)