User:Dinosaurseatpancakes/Draft of Endometriosis

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Last edited: Dinosaurseatpancakes (talk) 14:46, 11 September 2017 (UTC)


Endometriosis is a condition in which the layer of tissue that normally covers the inside of the uterus, grows outside it.[1][2] Most often this is on the ovaries, fallopian tubes, and tissue around the uterus and ovaries; however, in rare cases it may also occur in other parts of the body.[3] The main symptoms are pelvic pain and infertility.[4] Nearly half of those affected have chronic pelvic pain, while in 70% pain occurs during menstruation.[4] Pain during sex is also common.[4] Infertility occurs in up to half of women affected.[4] Less common symptoms include urinary or bowel symptoms.[4] About 25% of women have no symptoms.[4] Endometriosis can have both social and psychological effects.[5]

The cause is not entirely clear.[4] Risk factors include having a family history of the condition.[3] The areas of endometriosis bleed each month, resulting in inflammation and scarring.[3][4] The growths due to endometriosis are not cancer.[3] Diagnosis is usually based on symptoms in combination with medical imaging.[3] Biopsy is the most sure method of diagnosis.[3] Other causes of similar symptoms include pelvic inflammatory disease, irritable bowel syndrome, interstitial cystitis, and fibromyalgia.[4]

Tentative evidence suggests that the use of combined oral contraceptives reduces the risk of endometriosis.[6] Exercise and avoiding large amounts of alcohol may also be preventive.[3] There is no cure for endometriosis, but a number of treatments may improve symptoms.[4] This may include pain medication, hormonal treatments, or surgery.[3] The recommended pain medication is usually an NSAID such as naproxen.[3] Taking the active component of the birth control pill continuously or using an intrauterine device with progestogen may also be useful.[3] Gonadotropin-releasing hormone agonist may improve the ability of those who are infertile to get pregnant.[3] Surgical removal of endometriosis may be used to treat those whose symptoms are not manageable with other treatments.[3]

Endometriosis affected 10.8 million as of 2015.[7] Another estimate states about 6–10% of women are affected.[4] It is most common in those in their thirties and forties; however, it can begin in girls as early as 8 years old.[3][8] It results in few deaths.[9] Endometriosis was first determined to be a separate condition in the 1920s.[10] Before that time endometriosis and adenomyosis were considered together.[10] It is unclear who first described the disease.[10]



Moving stuff to the below subsections?

Signs and symptoms[edit]

Pelvic pain[edit]

Infertility[edit]

Other[edit]

Risk factors[edit]

Genetics[edit]

Environmental toxins[edit]

Pathophysiology[edit]

Formation[edit]

Retrograde menstruation theory[edit]

Other theories[edit]

Localization[edit]

Diagnosis[edit]

Laparoscopy[edit]

Staging[edit]

Markers[edit]

Histopathology[edit]

Pain quantification[edit]

Prevention[edit]

Management[edit]

Surgery[edit]

Hormones[edit]

Other medication[edit]

Comparison of interventions[edit]

Treatment of infertility[edit]

Prognosis[edit]

Complications[edit]

Epidemiology[edit]

History[edit]

Society and culture[edit]

References[edit]

  1. ^ "Endometriosis: Overview". www.nichd.nih.gov. Archived from the original on 18 May 2017. Retrieved 20 May 2017.
  2. ^ "Endometriosis: Condition Information". www.nichd.nih.gov. Archived from the original on 30 April 2017. Retrieved 20 May 2017.
  3. ^ a b c d e f g h i j k l m "Endometriosis". womenshealth.gov. 13 February 2017. Archived from the original on 13 May 2017. Retrieved 20 May 2017.
  4. ^ a b c d e f g h i j k Bulletti, Carlo; Coccia, Maria Elisabetta; Battistoni, Silvia; Borini, Andrea (2010-08-01). "Endometriosis and infertility". Journal of Assisted Reproduction and Genetics. 27 (8): 441–447. doi:10.1007/s10815-010-9436-1. ISSN 1573-7330. PMC 2941592. PMID 20574791.
  5. ^ Culley, Lorraine; Law, Caroline; Hudson, Nicky; Denny, Elaine; Mitchell, Helene; Baumgarten, Miriam; Raine-Fenning, Nick (1 November 2013). "The social and psychological impact of endometriosis on women's lives: a critical narrative review". Human Reproduction Update. 19 (6): 625–639. doi:10.1093/humupd/dmt027. ISSN 1460-2369. PMID 23884896.
  6. ^ Vercellini, Paolo; Eskenazi, Brenda; Consonni, Dario; Somigliana, Edgardo; Parazzini, Fabio; Abbiati, Annalisa; Fedele, Luigi (1 March 2011). "Oral contraceptives and risk of endometriosis: a systematic review and meta-analysis". Human Reproduction Update. 17 (2): 159–170. doi:10.1093/humupd/dmq042. ISSN 1460-2369. PMID 20833638.
  7. ^ Cite error: The named reference GBD2015Pre was invoked but never defined (see the help page).
  8. ^ McGrath, Patrick J.; Stevens, Bonnie J.; Walker, Suellen M.; Zempsky, William T. (2013). Oxford Textbook of Paediatric Pain. OUP Oxford. p. 300. ISBN 9780199642656. Archived from the original on 2017-09-10.
  9. ^ GBD 2013 Mortality and Causes of Death Collaborators (17 December 2014). "Global, regional, and national age-sex specific all-cause and cause-specific mortality for 240 causes of death, 1990-2013: a systematic analysis for the Global Burden of Disease Study 2013". Lancet. 385 (9963): 117–71. doi:10.1016/S0140-6736(14)61682-2. PMC 4340604. PMID 25530442. {{cite journal}}: |author= has generic name (help)CS1 maint: numeric names: authors list (link)
  10. ^ a b c Brosens I (2012). Endometriosis: Science and Practice. John Wiley & Sons. p. 3. ISBN 9781444398496.