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Superspreader[edit]

A superspreader is an unusually contagious organism infected with a disease. In the context of a human-borne illness, a superspreader is an individual who is more likely to infect others, compared with a typical infected person. Such superspreaders are of particular concern in epidemiology.

Some cases of superspreading conform to the 80/20 rule,[1] where approximately 20% of infected individuals are responsible for 80% of transmissions, although superspreading can still be said to occur when superspreaders account for a higher or lower percentage of transmissions.[2] In epidemics with such superspreader events (SSEV), the majority of individuals infect relatively few secondary contacts.[citation needed]

SSEVs are shaped by multiple factors including a decline in herd immunity, nosocomial infections, virulence, viral load, misdiagnosis, airflow dynamics, immune suppression, and co-infection with another pathogen.[3]

  1. ^ Galvani, Alison P.; May, Robert M. (2005). "Epidemiology: Dimensions of superspreading". Nature. 438 (7066): 293–95. Bibcode:2005Natur.438..293G. doi:10.1038/438293a. PMC 7095140. PMID 16292292.
  2. ^ Lloyd-Smith, JO; Schreiber, SJ; Kopp, PE; Getz, WM (2005). "Superspreading and the effect of individual variation on disease emergence". Nature. 438 (7066): 355–59. Bibcode:2005Natur.438..355L. doi:10.1038/nature04153. PMC 7094981. PMID 16292310.
  3. ^ Stein, Richard A. (2011). "Superspreaders in Infectious Disease". International Journal of Infectious Diseases. 15 (8): 510–13. doi:10.1016/j.ijid.2010.06.020. PMC 7110524. PMID 21737332. The minority of individuals who infect disproportionately more susceptible contacts, as compared to most individuals who infect few or no others, became known as super-spreaders, and their existence is deeply rooted in history: between 1900 and 1907, Typhoid Mary infected 51 individuals, three of whom died, even though she only had an asymptomatic infection.


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Disease cluster[edit]

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