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Chemotherapy
Chemotherapy drugs such as Dacarbazine have been the backbone of metastatic melanoma treatment since FDA approval in 1975 however, its efficacy in terms of survival has never been proven in an RCT.[1]
In people with locally advanced cutaneous malignancies and sarcoma, isolated limb infusion (ILI) has been found to be a minimally invasive and well-tolerated procedure for delivering regional chemotherapy.[2][3]
- ^ Pasquali, Sandro; Hadjinicolaou, Andreas V; Chiarion Sileni, Vanna; Rossi, Carlo Riccardo; Mocellin, Simone (2018-02-06). "Systemic treatments for metastatic cutaneous melanoma". Cochrane Database of Systematic Reviews. doi:10.1002/14651858.cd011123.pub2. ISSN 1465-1858.
- ^ O’Donoghue, Cristina; Perez, Matthew C.; Mullinax, John E.; Hardman, Danielle; Sileno, Sean; Naqvi, Syeda Mahrukh Hussnain; Kim, Youngchul; Gonzalez, Ricardo J.; Zager, Jonathan S. (2017-10-10). "Isolated Limb Infusion: A Single-Center Experience with Over 200 Infusions". Annals of Surgical Oncology. 24 (13): 3842–3849. doi:10.1245/s10434-017-6107-9. ISSN 1068-9265.
- ^ Coventry, Brendon; Giles, Mitchell (2013-08). "Isolated limb infusion chemotherapy for melanoma: an overview of early experience at the Adelaide Melanoma Unit". Cancer Management and Research. 5: 243. doi:10.2147/cmar.s45746. ISSN 1179-1322. PMC 3753062. PMID 23990731.
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[edit]Looks good so far.
- Remember to not use "patients" (rather refer to "people" in Wikipedia).
- Is RCT defined earlier in the text? If not define it in your text.
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