User:Mr. Ibrahem/Aminolevulinic acid
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| Clinical data | |
|---|---|
| Trade names | Levulan, NatuALA, Ameluz, others |
| Other names | 5-aminolevulinic acid hydrochloride (5ALA0 |
| AHFS/Drugs.com | Monograph |
| MedlinePlus | a607062 |
| License data |
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| Routes of administration | Topical, By mouth |
| Legal status | |
| Legal status |
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| Identifiers | |
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| Chemical and physical data | |
| Formula | C5H9NO3 |
| Molar mass | 131.131 g·mol−1 |
| 3D model (JSmol) | |
| Melting point | 118 °C (244 °F) |
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| (verify) | |
δ-Aminolevulinic acid (dALA, δ-ALA), also known as 5-aminolevulinic acid (5ALA), is a medication used to help visualize cancer tissue during surgery for glioma.[2] It is also used to treat actinic keratoses and basal cell cancer.[1] It is taken by mouth or applied to the skin.[2][1]
Common side effects when taken by mouth include nausea, fever, low blood pressure, liver problems, and diarrhea.[2] Common side effects when applied to the skin include redness, irritation, itchiness, and skin peeling.[1] Safety in pregnancy is unclear.[3] When applied to the skin, it works by making the area sensitive to light, such that when exposed it results in cell death.[1]
δ-Aminolevulinic acid was approved for medical use in the United States in 1999 and Europe in 2011.[2][1] In the United States 2 grams of gel costs about 340 USD as of 2022.[4]
References[edit]
- ^ a b c d e f g "Ameluz". Archived from the original on 20 November 2021. Retrieved 14 January 2022.
- ^ a b c d e f "DailyMed - GLEOLAN- aminolevulinic acid hydrochloride powder, for solution". dailymed.nlm.nih.gov. Archived from the original on 24 March 2021. Retrieved 14 January 2022.
- ^ "Aminolevulinic acid topical Use During Pregnancy". Drugs.com. Archived from the original on 26 January 2021. Retrieved 14 January 2022.
- ^ "Ameluz Prices, Coupons & Patient Assistance Programs". Drugs.com. Archived from the original on 23 April 2021. Retrieved 14 January 2022.