User:Mr. Ibrahem/Diroximel fumarate
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| Clinical data | |
|---|---|
| Trade names | Vumerity |
| Other names | ALKS-8700 |
| AHFS/Drugs.com | Monograph |
| MedlinePlus | a620002 |
| License data | |
| Routes of administration | By mouth |
| Legal status | |
| Legal status | |
| Chemical and physical data | |
| Formula | C11H13NO6 |
| Molar mass | 255.226 g·mol−1 |
| 3D model (JSmol) | |
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Diroximel fumarate, sold under the brand name Vumerity, is a medication used to treat relapsing forms of multiple sclerosis (MS).[1] This includes clinically isolated syndrome, relapsing-remitting disease, and active secondary progressive disease.[1] It is taken by mouth.[1]
Common side effects include flushing, abdominal pain, diarrhea, and nausea.[1] Other side effects may include anaphylaxis, progressive multifocal leukoencephalopathy, herpes zoster, liver problems, and low lymphocytes.[1] Use in pregnancy may harm the baby.[2] It works after the body converts it into monomethyl fumarate (MMF).[3]
Diroximel fumarate was approved for medical use in the United States in 2019.[3] While it was approved in Europe and the United Kingdom in 2021 it is not yet commercially available.[3] In the United States it costs about 7,900 USD per day as of 2021.[4]
References
[edit]- ^ a b c d e f g h "Vumerity- diroximel fumarate capsule". DailyMed. Archived from the original on 5 February 2021. Retrieved 1 February 2021.
- ^ "Diroximel fumarate Pregnancy and Breastfeeding Warnings". Archived from the original on 14 February 2021. Retrieved 26 December 2021.
- ^ a b c "Vumerity · Relapsing remitting multiple sclerosis (MS)". Archived from the original on 19 May 2021. Retrieved 26 December 2021.
- ^ "Vumerity Prices, Coupons and Patient Assistance Programs". Retrieved 26 December 2021.