User:Mr. Ibrahem/Iron sucrose

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Mr. Ibrahem/Iron sucrose
Clinical data
Trade namesVenofer, others
AHFS/Drugs.comMonograph
MedlinePlusa614017
License data
Pregnancy
category
  • AU: B3
Routes of
administration		Intravenous
Legal status
Legal status
Identifiers
  • disodium;(2R,3R,4S,5S,6R)-2-[(2S,3S,4S,5R)-3,4-dihydroxy-2,5-bis(hydroxymethyl)oxolan-2-yl]oxy-6-(hydroxymethyl)oxane-3,4,5-triol;iron(3+);oxygen(2-);hydroxide;trihydrate
Chemical and physical data
FormulaC12H29Fe5Na2O23
Molar mass866.546 g·mol−1
3D model (JSmol)
  • C(C1C(C(C(C(O1)OC2(C(C(C(O2)CO)O)O)CO)O)O)O)O.O.O.O.[OH-].[O-2].[O-2].[O-2].[O-2].[O-2].[O-2].[O-2].[O-2].[Na+].[Na+].[Fe+3].[Fe+3].[Fe+3].[Fe+3].[Fe+3]
  • InChI=1S/C12H22O11.5Fe.2Na.4H2O.8O/c13-1-4-6(16)8(18)9(19)11(21-4)23-12(3-15)10(20)7(17)5(2-14)22-12;;;;;;;;;;;;;;;;;;;/h4-11,13-20H,1-3H2;;;;;;;;4*1H2;;;;;;;;/q;5*+3;2*+1;;;;;8*-2/p-1/t4-,5-,6-,7-,8+,9-,10+,11-,12+;;;;;;;;;;;;;;;;;;;/m1.................../s1
  • Key:FWZTTZUKDVJDCM-CEJAUHOTSA-M

Iron sucrose (IS), sold under the brand name Venofer, is a medication used to treat iron deficiency anemia in people with chronic kidney disease.[1] In this group it works better than iron by mouth.[1] It is given by gradual injection into a vein.[1]

Common side effects include nausea, diarrhea,low blood pressure, itchiness, joint pain, and swelling.[1] Other side effects may include anaphylaxis.[1] It may have less side effects than iron dextran.[1] Iron sucrose replaces iron in the blood to foster red blood cell production.

Iron sucrose was approved for medical use in the United States in 2000; however, has been previously used in Europe.[2][3] In the United Kingdom 100 mg costs the NHS about £10 as of 2021.[4] This amount in the United States is about 60 USD.[5]

References[edit]

  1. ^ a b c d e f g h "Iron Sucrose Monograph for Professionals". Drugs.com. Archived from the original on 12 August 2021. Retrieved 28 November 2021.
  2. ^ Auerbach M, Ballard H (2010-12-04). "Clinical use of intravenous iron: administration, efficacy, and safety". Hematology. American Society of Hematology. Education Program. 2010 (1): 338–47. doi:10.1182/asheducation-2010.1.338. PMID 21239816.
  3. ^ Cançado RD, Muñoz M (2011). "Intravenous iron therapy: how far have we come?". Revista Brasileira de Hematologia e Hemoterapia. 33 (6): 461–9. doi:10.5581/1516-8484.20110123. PMC 3459360. PMID 23049364.
  4. ^ BNF 81: March-September 2021. BMJ Group and the Pharmaceutical Press. 2021. p. 1068. ISBN 978-0857114105.
  5. ^ "Venofer Prices, Coupons & Patient Assistance Programs". Drugs.com. Archived from the original on 19 January 2021. Retrieved 28 November 2021.
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