User:Mr. Ibrahem/Isavuconazonium
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| Clinical data | |
|---|---|
| Trade names | Cresemba |
| Other names | Isavuconazonium sulfate |
| AHFS/Drugs.com | Monograph |
| Pregnancy category |
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| Routes of administration | By mouth, intravenous (IV) |
| Drug class | Antifungal (triazole)[2] |
| Legal status | |
| Legal status | |
| Chemical and physical data | |
| Formula | C35H35F2N8O5S |
| Molar mass | 717.77 g·mol−1 |
| 3D model (JSmol) | |
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  (what is this?) (verify) | |
Isavuconazonium, sold under the brand name Cresemba, is a medication used to treat invasive aspergillosis and mucormycosis.[4][3] For mucormycosis, it is used when amphotericin B is not suitable.[5] It may be taken by mouth or given by gradual injection into a vein.[3]
Common side effects include liver problems, nausea, shortness of breath, abdominal pain, diarrhea, headache, low potassium and rash.[4] Other side effects may include anaphylaxis and short QT.[3][6] Use in pregnancy may harm the baby.[3] It is a antifungal medication of the triazole class and works after being converted into isavuconazole in the body.[2]
Isavuconazonium was approved for medical use in the United States and Europe in 2015.[6][4] In the United Kingdom a vial of 200 mg cost the NHS about £300 as of 2021.[5] This amount in the United States costs about 350 USD.[7]
References[edit]
- ^ a b "Isavuconazonium (Cresemba) Use During Pregnancy". Drugs.com. 31 January 2020. Archived from the original on 2 December 2020. Retrieved 26 August 2020.
- ^ a b Wilkes, Gail M.; Barton-Burke, Margaret (2019). 2020-2021 Oncology Nursing Drug Handbook. Jones & Bartlett Learning. pp. 1874–1876. ISBN 978-1-284-17132-7. Archived from the original on 2021-09-05. Retrieved 2021-09-05.
- ^ a b c d e f "Cresemba- isavuconazonium sulfate capsule Cresemba- isavuconazonium sulfate injection, powder, lyophilized, for solution". DailyMed. 2 December 2019. Archived from the original on 30 March 2021. Retrieved 26 August 2020.
- ^ a b c d e "Cresemba". Archived from the original on 10 August 2020. Retrieved 28 November 2021.
- ^ a b BNF 81: March-September 2021. BMJ Group and the Pharmaceutical Press. 2021. p. 635. ISBN 978-0857114105.
- ^ a b "Isavuconazonium Monograph for Professionals". Drugs.com. Archived from the original on 25 January 2021. Retrieved 26 November 2021.
- ^ "Cresemba Prices, Coupons & Patient Assistance Programs". Drugs.com. Archived from the original on 10 April 2020. Retrieved 28 November 2021.