User:Mr. Ibrahem/Keloid

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Keloid
Other namesKeloid disorder, keloidal scar[1]
Bulky keloid forming at the site of abdominal surgery
Pronunciation
SpecialtyDermatology
SymptomsAreas of scaring which is firm, raised, and rubbery[2]
CausesGenetic and environmental factors[2]
Risk factorsDarker skin[2]
Diagnostic methodExamination, may be confirmed by biopsy[2]
Differential diagnosisDermatofibroma, hypertrophic scar[2]
TreatmentTopical steroids, cryotherapy, surgical excision, radiation therapy, laser therapy[2][3]
Frequency4 to 16% (people with darker skin)[2]

A keloid is an areas of scaring which is firm, raised, and rubbery and larger than the original wound.[2] The color may be the same as the skin, red, or darker.[2] There may also be itching, burning, or pain.[2] They may not form until months after the initial injury.[4] These lesions are non cancerous.[2]

They occur due to a combination of genetic and environmental factors.[2] In those who are at risk, they can occur after any degree of injury to the skin.[2] The underlying mechanism involves abnormal wound healing.[2] Diagnosis is generally based on examination, though may be confirmed by biopsy.[2] It differs from a hypertrophic scar in that it grows beyond the site of the original wound.[2]

Treatment is difficult.[2] Efforts may include corticosteroids, cryotherapy, surgical excision, radiation therapy, and laser therapy.[2][3] Rates are 4.5 to 16% in people with darker skin.[2] People between the ages of 10 to 30 are more commonly affected.[4]

References[edit]

  1. ^ Rapini, Ronald P.; Bolognia, Jean L.; Jorizzo, Joseph L. (2007). Dermatology: 2-Volume Set. St. Louis: Mosby. p. 1499. ISBN 978-1-4160-2999-1.
  2. ^ a b c d e f g h i j k l m n o p q r s McGinty, S; Siddiqui, WJ (January 2020). "Keloid". PMID 29939676. {{cite journal}}: Cite journal requires |journal= (help)
  3. ^ a b Ogawa, Rei (2010). "The Most Current Algorithms for the Treatment and Prevention of Hypertrophic Scars and Keloids". Plastic and Reconstructive Surgery. 125 (2): 557–68. doi:10.1097/PRS.0b013e3181c82dd5. PMID 20124841.
  4. ^ a b "Keloid scars". nhs.uk. 26 April 2018. Retrieved 16 January 2021.