User:Mr. Ibrahem/Neomycin/polymyxin B/bacitracin

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Mr. Ibrahem/Neomycin/polymyxin B/bacitracin
A tube of Neosporin
Combination of
Polymyxin B sulfateAntibiotic
Neomycin sulfateAntibiotic
Bacitracin zincAntibiotic
Clinical data
Trade namesNeosporin, others
AHFS/Drugs.comProfessional Drug Facts
MedlinePlusa601098
License data
Routes of
administration		Topical, eye drops
Legal status
Legal status
  • US: OTC / Rx-only
  (verify)

Neomycin/polymyxin B/bacitracin, also known as triple antibiotic ointment, is a medication used to try to decrease the risk of infections following minor skin injuries and to treat superficial bacterial eye infections.[2][3] It contains three antibiotics: neomycin, polymyxin B, and bacitracin.[2] It is generally less preferred than bacitracin/polymyxin B.[4] It is either applied to the skin or used as eye drops.[2][3]

Common side effects include itchiness and skin rash.[1] More severe side effects may include hearing loss.[1] Use in pregnancy is generally not recommended.[1] It is relatively broad spectrum, being effective against both Gram-negative and Gram-positive bacteria.[3]

The combination was approved for medical use in the United States in 1971.[5] It is available over the counter in the United States.[1] In 2017, it was the 78th most commonly prescribed medication in the United States, with more than ten million prescriptions.[6][7] It is sold under the brand name Neosporin among others.[8]

References[edit]

  1. ^ a b c d e "Neomycin, polymyxin b, and bacitracin Topical Advanced Patient Information". Drugs.com. Archived from the original on 19 April 2019. Retrieved 19 April 2019.
  2. ^ a b c "DailyMed - neomycin, bacitracin, polymyxin b ointment". dailymed.nlm.nih.gov. Archived from the original on 11 July 2021. Retrieved 19 April 2019.
  3. ^ a b c "Neomycin and polymyxin B sulfates and bacitracin zinc ophthalmic ointment" (PDF). FDA. Archived (PDF) from the original on 14 April 2021. Retrieved 19 April 2019.
  4. ^ Woo, Teri Moser; Robinson, Marylou V. (2015). Pharmacotherapeutics For Advanced Practice Nurse Prescribers. F.A. Davis. p. 651. ISBN 9780803645813. Archived from the original on 2019-04-19. Retrieved 2019-04-19.
  5. ^ "Drugs@FDA: FDA Approved Drug Products". U.S. Food and Drug Administration (FDA). Archived from the original on 24 March 2021. Retrieved 19 April 2019.
  6. ^ "The Top 300 of 2020". ClinCalc. Archived from the original on 12 February 2021. Retrieved 11 April 2020.
  7. ^ "Bacitracin; Neomycin; Polymyxin B - Drug Usage Statistics". ClinCalc. Archived from the original on 25 January 2021. Retrieved 11 April 2020.
  8. ^ "Neosporin (topical) Uses, Side Effects & Warnings". Drugs.com. Archived from the original on 6 May 2021. Retrieved 19 April 2019.
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