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Jay S. Yadav, M.D., F.A.A.C.

Jay S. Yadav, M.D., F.A.A.C.
Born	29 October 1959 India
Citizenship	U.S.
Alma mater	College 1979- Yale University, New Haven, Conn; B.S. Molecular Biophysics & Biochemistry                                           Medical School 1983- West Virginia University Medical School, Morgantown, WV; Medical Degree Internship 1984- Univ. of California-Irvine, Irvine, CA; Internal Medicine Residencies 1987- Duke University Medical Center, Durham, North Carolina; Internal Medicine and Neurology Chief Residency 1988- Duke University Medical Center, Durham, North Carolina; Neurology Fellowships 1989- Dent Neurological Institute, Buffalo, New York; Neuroimaging 1996- University of Alabama at Birmingham, Birmingham, Alabama; Cardiology and Interventional Cardiology
Known for	Angioguard the first embolic protection device. SMART therapeutics the first neuroform microdelivery self-expanding technology for intracranial therapies. CardioMEMS the first and only FDA-approved heart failure monitoring system proven to significantly reduce heart failure hospital admissions and improve quality of life in NYHA class III patients.   Molybdenum-Rhenium (MoRe) alloy the first rhenium-based alloy to be approved for use in medical devices in the last 40 years.
Awards	·       American Heart Association Top Ten Scientific Advances, 2003 ·       Ellis Island Medal of Honor, 2004 ·       50 Best Doctors in the History of the Cleveland Clinic, 2011 ·       Ernst and Young Entrepreneur of the Year (healthcare), 2011 ·       Intel Innovation Award, 2011; his procedure for stroke treatment became a Class I recommendation of the American Heart Association and the American College of Cardiology, 2011 ·       American Heart Association Honoree, 2016
Scientific Career
Fields	Interventional Cardiology, Neurology, Medical Devices

Jay S. Yadav, MD, F.A.A.C.

Jay S. Yadav (29 October 1959) is an interventional cardiologist, neurologist, scientist and serial entrepreneur.

His best-known discoveries include Angioguard in 19XX, the first embolic protection device shown in clinical testing to achieve a relative stroke reduction of 70% during carotid stenting procedures. SMART therapeutics in XXX the first neuroform microdelivery self-expanding technology for intracranial therapies. CardioMEMS in 2012 the first and only FDA-approved heart failure monitoring system proven to significantly reduce heart failure hospital admissions and improve quality of life in NYHA class III patients. Molybdenum-Rhenium (MoRe) alloy the first rhenium-based alloy to be approved for use in medical devices in the last 40 years.

Early life and education

Born on 29 October 1959 in XXX, India, Jay is the first of three children of [Father’s name- DOB/DOD] and [Mother’s name- DOB].

Dr. Yadav attended Yale University in 1979 receiving a BS in Molecular Biophysics and Biochemistry then went to medical school at the West Virginia University in 1983 with an internship in internal medicine at University of California-Irvine and residency in neurology at Duke University from 1987-1988. In 1989 he underwent a neuroimaging fellowship at the Dent Neurological Institute in Buffalo, New York. In 1996 he underwent a cardiology and interventional cardiology fellowship at the University of Alabama at Birmingham.

College

1979- Yale University, New Haven, Conn; B.S. Molecular Biophysics & Biochemistry                                        

Medical School

1983- West Virginia University Medical School, Morgantown, WV; Medical Degree

Internship

1984- Univ. of California-Irvine, Irvine, CA; Internal Medicine

Residencies

1987- Duke University Medical Center, Durham, North Carolina; Internal Medicine and Neurology

Chief Residency

1988- Duke University Medical Center, Durham, North Carolina; Neurology

Fellowships

1989- Dent Neurological Institute, Buffalo, New York; Neuroimaging

1996- University of Alabama at Birmingham, Birmingham, Alabama; Cardiology and Interventional Cardiology

Research

·      Executive Committee, Sirolimus – SMART Stent SFA Trial JNJ

·      Chairman, Steering Committee, SAPPHIRE: Stenting and Angioplasty in Patients at High Risk for Endarterectomy; randomized trial comparing endarterectomy to carotid stenting, 800 patients.

·      Principal Investigator, ARCHER Carotid Stent Trial.

·      Principal Investigator, Cleveland Clinic Registry on Carotid Stenting for High Surgical Risk Patients.

·      Co-Principal Investigator, CORAL Renal Study, NIH

·      Principal Investigator, ACT I Stenting versus Endarterectomy Trial, Abbott Vascular Devices.

·      Principal Investigator, Clopidogrel for High Atherothrombotic Risk and Ischemic Stabilization, Management and Avoidance (CHARISMA), Sanofi and Bristol-Myers Squibb.

·      Principal Investigator, RESIST Renal Artery Stenting Study, Medical College of Ohio

·      Principal Investigator, Multicenter Clinical Evaluation of Carotid Stenting with Protection, Cordis

·      Principal Investigator, Carotid Revascularization with ev3 Arterial Technology Revolution (CREATE), ev3

·      Principal Investigator, Cerebrovascular Interventional Database Registry

·      Principal Investigator, Maveric carotid stent system trial, Medtronic

·      Principal Investigator, ARCHER long term follow up, Guidant

·      Principal Investigator, Carotid Artery Stenting with Emboli Protection Surveillance –                        Post Market Study (CASES-PMS), Cordis

·      Principal Investigator, Post-Market Study of Guidant Carotid Stent Systems and      Embolic Protection Systems (CAPTURE), Guidant

Awards and honors

His scientific and entrepreneurial work has been widely recognized, having received multiple honors including: American Heart Association Top Ten Scientific Advances, 2003; Ellis Island Medal of Honor, 2004; 50 Best Doctors in the History of the Cleveland Clinic, 2011; Ernst and Young Entrepreneur of the Year (healthcare), 2011; Intel Innovation Award, 2011; his procedure for stroke treatment became a Class I recommendation of the American Heart Association and the American College of Cardiology, 2011; American Heart Association Honoree, 2016.

Patents

Dr. Yadav has been a prolific inventor across a number of disciplines including stent design, emboli prevention devices, cardiac valves, left ventricular assist devices, contrast mediated nephrotoxicity, wireless implants for heart failure, hydrocephalus and surgical navigation.

	PUB. APP. NO.	Title	Date Filed	Description
1	6,083,258	Locking stent	5/28/1998	An expandable intraluminal stent able to resist axial compression, comprising a body portion having a generally cylindrical structure formed by a series of interconnected bars or struts, at least one of said struts being formed of two portions having overlapping free ends; and a plurality of teeth projecting on adjacent surfaces of said overlapping free ends; whereby said stent is expanded to allow said two portions of said at least one strut to overlap at said free ends, whereby said teeth on said adjacent surfaces of said overlapping free ends of said struts engage one another to retain said stent in its expanded shape.
2	6,755,846	Vascular filter	8/6/1998	A removable vascular filter device for blocking micro-and macro-emboli while allowing continued perfusion of blood, comprises a guidewire having distal and proximal portions, wherein there is a recess in the distal portion and a filter comprising a flexible filter membrane and a filter membrane support structure. The filter membrane has a fixed inner portion and a free outer portion, wherein the filter membrane fixed inner portion is movably attached toward the distal end of the guidewire recess and wherein the filter membrane free outer portion is positioned in the recess when the filter membrane is in a collapsed state. A deploying means causes the filter membrane proximal end portion to assume a position substantially normal to the longitudinal axis of the guidewire.
3	20040092790	Hydraulically actuated artificial muscle for ventricular assist	8/3/2003	A ventricular assist device comprises a sheet of hydraulically actuated material that can be affixed to prescribed locations on the surface of the heart to assist areas of the heart that do not contract normally. The material is comprised of a network of contractible unit cells that individually contract when fluid is pumped into them. These unit cells are connected together in a network that causes the sheet to contract radially inward. This contraction causes the sheet to transmit forces to the heart to assist in its natural contraction. A sensing function coordinates the contraction of the sheet with the contraction of the heart. The change in shape of the device is accomplished by distributing pressurized fluid throughout the spaces of the device by way of a network of channels. When pressure is removed from the fluid system, it assumes a deenergized "rest" position in which it does not transmit any forces to the surface of the heart. This property of the device prevents the device from inhibiting the heart's natural contractions in the event of a failure of the device or a loss of hydraulic power.
4	20070156233	Percutaneous atrioventricular valve and method of use	8/24/2006	An apparatus for percutaneously replacing a diseased cardiac valve includes an expandable support member for positioning in an atrial chamber. The expandable support member includes at least one anchoring portion for anchoring in at least one opening that extends from the atrial chamber and a main body portion located adjacent the at least one anchoring portion. The main body portion has a cage-like structure and is adapted to conform to a size and shape of the atrial chamber. An expandable ring is selectively connected to the main body portion. The expandable ring is adapted to engage an annulus of the diseased cardiac valve. A prosthetic valve is attached to the expandable ring. The prosthetic valve is adapted to replace the diseased cardiac valve. A method for percutaneously replacing a diseased cardiac valve is also described.
5	20080213433	Fluid compositions comprising polyphenols and methods for making and packaging the same	6/13/2007	The present invention provides a number of compositions, including non-alcoholic and non-fermented aqueous solutions comprising trans-resveratrol and/or other polyphenols. In one aspect, the present invention provides retail or commercially available beverages comprising trans-resveratrol and/or other polyphenols.
6	20080228124	RADIOGRAPHIC CONTRAST MEDIA CAPTURE MATERIAL	2/15/2008	The present invention relates to materials, coatings, apparatus, and methods for removing radiocontrast agent from a patient. In accordance with one aspect of the invention, molecular imprinting technologies are utilized to create a safe, predictable and reliable medium for removal of nephrotoxic contrast agent from body fluids of a patient, such as the bloodstream. In accordance with certain aspects of the present invention, the contrast agent can be removed without mechanical filtering or any other mechanically damaging technique affecting the blood matrix. The molecularly imprinted medium (MIM) can be used to extract the contrast agent from the blood either intra- or extracorporeally.
7	20100262021	Hypertension system and method	1/27/2009	Disclosed are hypertension systems and related methods that include a blood pressure sensor located or implanted under the skin of a patient, and electronics, which may have the size and shape of a wrist watch, for example, that monitors the blood pressure of the patient by communicating with the implanted sensor.
8	20100022896	VENTRICULAR SHUNT SYSTEM AND METHOD	7/24/2009	A ventricular shunt systems and methods of preventing hydrocephalus are described herein. In one aspect, the ventricular shunt system has at least one pressure sensor that is configured to be selectively electromagnetically coupled to an ex-vivo source of RF energy and is variable in response to the pressure in a patient's ventricle.
9	20130245469	Pulmonary Arterial Hemodynamic Monitoring for Chronic Obstructive Pulmonary Disease Assessment and Treatment	3/15/2013	Provided herein are methods for assessing, treating, and for developing new treatments for COPD. Methods can involve obtaining one or more PA hemodynamic readings from a subject with COPD, processing the PA hemodynamic readings to obtain one or more PA hemodynamic parameters, and using the one or more PA hemodynamic parameters to assess, treat, and/or develop new treatments for COPD. The methods can optionally be used to evaluate the progress of (COPD) in a subject, or to predict an outcome in a subject having COPD.
10	20160360997	SYSTEMS AND METHODS FOR MEASURING RELATIVE ORIENTATION AND POSITION OF ADJACENT BONES	8/23/2016	A method for estimating leg length and offset, comprises registering an anatomic coordinate frame associated with a patient's pelvis. The method also comprises measuring a first position of a femur relative to the patient's pelvis. The method further comprises receiving, from magnetic and orientation sensors, information indicative of a change in a position of the femur relative to the pelvis of the patient's pelvis. Alternatively, the method further comprises receiving, from light and orientation sensors, information indicative of a change in a position of the femur relative to the pelvis of the patient's pelvis. The method also comprises determining at least one of a leg length and an offset based on the first position and the change in position.

Personal life

On XX, XXXX, XXXX, Jay Yadav married, Marshalla XXX of XXX. He currently resides in Atlanta Georgia.  They have four children, Nevin Yadav of XXX, Chethan Yadav of XXX, Priya Yadav of XXX, Daven Yadav of XXX

Published Works

Manuscripts

1.     Yadav JS, Perfect J, Friedman AH:  Successful treatment of cryptococcal ventriculo-atrial shunt infection with systemic therapy alone.  Neurosurgery 1988; 23: 372-373.

2.      Yadav JS, Roubin G.: Coronary stenting for treatment of abrupt or threatened closure complicating percutaneous transluminal coronary angioplasty.  Coronary Artery Disease 1994;5: 564-570.

3.      Yadav JS, Roubin GS, King P, Iyer S, Vitek J. Angioplasty and stenting for restenosis after carotid endarterectomy. Initial experience Stroke 1996; 27: 2075-2079.

4.      Roubin GS, Yadav JS, Iyer SS, Vitek J.  Carotid Stent-Supported Angioplasty: a neurovascular intervention to prevent stroke.  American Journal of Cardiology  1996; 78(3A): 8-12.

5.      Goods CM, Liu MW, Iyer SS, Yadav JS, al-Shaibi KF, Dean LS, Roubin GS.  A cost analysis of coronary stenting without anticoagulation versus stenting with anticoagulation using warfarin.  American Journal of Cardiology 1966;78: 334-336

6.      Roubin GS, Yadav JS, Iyer S, King P, Vitek J. Concern about safety of carotid angioplasty (letter).  Stroke 1996; 27: 1130-1131.

7.      Goods CM, Al-Shaibi KF, Yadav JS, Liu MW, Negus BH, Iyer SS, Dean LS, Jain SP, Baxley WA, Parks JM, Sutor RJ, Roubin GS. Utilization of the coronary balloon-expandable coil stent without anticoagulation or intravascular ultrasound.  Circulation 1996;93: 1803-1808.

8.     Goods CM.  Mathur A. Liu MW.  Yadav JS.  Al-Shaibi KF. Dean LS.  Iyer SS. Parks JM.  Roubin GS.  Intracoronary stenting using slotted tubular stents with intravascular ultrasound and anticoagulation.  Catheterization & Cardiovascular Diagnosis 1996; 39(4):341-345.

9.      Jain SP, Roubin GS, Iyer SS, Saddekni S, Yadav JS. Closure of an iatrogenic femoral artery pseudoaneurysm by transcutaneous coil embolization.  Catheterization & Cardiovascular Diagnosis 1996; 39(3):317-319.

10.   Goods CM, Al-Shaibi KF, Liu MW, Yadav JS, Mathur A, Jain SP, Dean LS, Iyer SS, Parks JM, Roubin GS. Comparison of aspirin alone versus aspirin plus ticlopidine after coronary artery stenting. American Journal of Cardiology 1996; 78(9):1042-1044.

11.    Gomez C.  Kinkel P. Masdeu J.  McKinney W.  Polachini I Jr.  Tegeler C. Yadav J. American Academy of Neurology guidelines for credentialing in neuroimaging.  Report from the task force on updating guidelines for credentialing in neuroimaging. Neurology, 1997; 49(6):1734-1737

12.   Mathur A.  Dorros G. Iyer SS.  Vitek JJ.  Yadav JS. Roubin GS. Palmaz stent compression in patients following carotid artery stenting.  Catheterization & Cardiovascular Diagnosis 1997;41(2):137-140.

13.   Jain SP, Liu MW, Dean LS, Babu R, Goods CM, Yadav JS, Al-Shaibi KF, Mathur A, Iyer SS, Parks JM, Baxley WA, Roubins GS. Comparison of balloon angioplasty versus debulking devices versus stenting in right coronary ostial lesions. American Journal of Cardiology 1997; 79(10):1334-1338.

14.   Robbin ML, Lockhart ME, Weber TM, Vitek JJ, Smith JK, Yadav JS, Mathur A, Iyer SS, Roubin GS.  Carotid Artery Stents: Early and intermediate follow-up with Doppler US.  Radiology 1997;205(3): 749-756

15.   Mathur A, Roubin GS, Yadav JS, Iyer SS, Vitek J. Combined coronary and bilateral carotid stenting: a case report.  Catheterization & Cardiovascular Diagnosis 1997; 40: 202-206.

16.   Mathur A, Liu MW, Goods CM, Al-Shaibi KF, Parks MJ, Iyer SS, Jain SP, Yadav JS, Baxley WA, Dean LS.  Results of elective stenting of branch-ostial lesions. American Journal of Cardiology  1997;79(4):472-474.

17.   Yadav JS, Roubin GS, Iyer S, Vitek J, King P, Jordan WD, Fisher WS. Elective stenting of the extracranial carotid arteries.  Circulation 1997; 95: 376-381.

18.   Wholey MH, Wholey M, Bergeron P, Yadav JS et al, Current global status carotid artery stent placement.  Catheterization & Cardiovascular Diagnosis 1998; 44:1-6.

19.   Mathur A, Roubin GS, Gomez CR, Iyer SS, Wong PM, Piamsonbon C, Yadav JS, Dean LS, Vitek JJ, Elective carotid artery stenting in the presence of contralateral occlusion.  American Journal of Cardiology 1998; 81:1315-1317.

20.  Mathur A, Roubin GS, Iyer SS, Piamsonbon C, Liu MW, Gomez CR, Yadav JS, Chastin HD, Fox LM, Dean LS, Vitek JJ.  Predictors of stroke complicating carotid artery stenting. Circulation 1998;97:1239-1245.

21.   Yadav JS. Treatment of carotid atherosclerotic disease: carotid endarterectomy or stenting? CVI On-Line 1999 May.

22.  Bajzer CT, Yadav JS. Strategies and techniques for carotid angioplasty with adjunctive stenting. Carotid Intervention 1999;1(2):34-40.

23.  Yadav JS. SAPPHIRE Trial: concepts and outline. Endocardiovascular Multimedia Magazine 2000;4:77-81.

24.  Yadav JS. Intracranial use of direct stenting for basilar artery stenosis. Journal Watch Neurology 2000 Feb;

25.  Wholey MH, Wholey M, Mathias K, Roubin GS, Diethrich EB, Henry M, Bailey S, Bergeron P, Dorros G, Eles G, Gaines P, Gomez CR, Gray B, Guimaraens J, Higashida R, Ho DS, Katzen B, Kambara A, Kumar V, Laborde JC, Leon M, Lim M, Londero H, Mesa J, Musacchio A, Myla S, Ramee S, Rodriquez A, Rosenfield K, Sakai N, Shawl F, Sievert H, Teitelbaum G, Theron JG, Vaclav P, Vozzi C, Yadav JS, Yoshimura SI. Global experience in cervical carotid artery stent placement. Catheterization and Cardiovascular Interventions 2000 Jun;50(2):160-167.

26.  White CJ, Gomez CR, Iyer SS, Wholey M, Yadav JS. Carotid stent placement for extracranial carotid artery disease: current state of the art. Catheterization and Cardiovascular Interventions 2000 Nov;51(3):339-346.

27.   Topol EJ, Yadav JS. Recognition of the importance of embolization in atherosclerotic vascular disease. Circulation 2000 Feb 8;101(5):570-580.

28.  Silver MJ, Yadav JS, Wholey M. Intermediate outcome after carotid stenting: what should we expect? Seminars in Vascular Surgery 2000 Jun;13(2):130-138.

29.  Ouriel K, Yadav JS. Carotid angioplasty and stenting: a personal perspective. Advances in Vascular Surgery 2000;8:19-39.

30.  New G, Roubin GS, Iyer SS, Vitek JJ, Wholey MH, Diethrich EB, Hopkins LN, Hobson RW, Leon MB, Myla SV, Shawl F, Ramee SR, Yadav JS, Rosenfield K, Liu MW, Gomez CR, Al-Mubarak N, Gray WA, Tan WA, Goldstein JE, Stack RS. Safety, efficacy, and durability of carotid artery stenting for restenosis following carotid endarterectomy: a multicenter study. Journal of Endovascular Therapy 2000 Oct;7(5):345-352.

31.   Mukherjee D, Reginelli JP, Moliterno DJ, Yadav JS, Schneider JP, Raymond R, Whitlow PL, Franco I, Topol EJ, Ellis SG. Unexpected mortality reduction with abciximab for in-stent restenosis. Journal of Invasive Cardiology 2000 Nov;12(11):540-544.

32.  Mukherjee D, Yadav JS. Carotid and cerebrovascular disease. Cardiology in Review 2000 Nov-Dec;8(6):322-332.

33.  Cura FA, Kapadia SR, L'Allier PL, Schneider JP, Kreindel MS, Silver MJ, Yadav JS, Simpfendorfer CC, Raymond RR, Tuzcu EM, Franco I, Whitlow PL, Topol EJ, Ellis SG. Safety of femoral closure devices after percutaneous coronary interventions in the era of glycoprotein IIb/IIIa platelet blockade. American Journal of Cardiology 2000 Oct 1;86(7):780-782.

34.  Bhatt DL, Kapadia SR, Yadav JS, Topol EJ. Update on clinical trials of antiplatelet therapy for cerebrovascular diseases. Cerebrovascular Diseases 2000 Nov;10(Suppl 5):34-40.

35.  Ziada KM, Roffi M, Yadav JS. Percutaneous stenting of a vertebral artery supplying the entire brain. Circulation 2001 Mar 20;103(11):e61.

36.  Ziada KM, Kapadia SR, Yadav JS. Expanding the indications for carotid stenting: radiation-induced extracranial carotid artery disease. Carotid Intervention 2001;3(2):34-38.

37.   Yadav JS. Interventional advances in long-term stroke prevention. Journal of Stroke and Cerebrovascular Diseases 2001 Mar 1;10(2B):24-29.

38.  Yadav JS. Management practices in carotid stenting. Cerebrovascular Diseases 2001 Apr;11(Suppl 2):18-22.

39.  Veith FJ, Amor M, Ohki T, Beebe HG, Bell PR, Bolia A, Bergeron P, Connors JJ3, Diethrich EB, Ferguson RD, Henry M, Hobson RW2, Hopkins LN, Katzen BT, Matthias K, Roubin GS, Theron J, Wholey MH, Yadav SS. Current status of carotid bifurcation angioplasty and stenting based on a consensus of opinion leaders. Journal of Vascular Surgery 2001 Feb;33(2 Suppl):S111-S116.

40.  Roubin GS, New G, Iyer SS, Vitek JJ, Al-Mubarak N, Liu MW, Yadav J, Gomez C, Kuntz RE. Immediate and late clinical outcomes of carotid artery stenting in patients with symptomatic and asymptomatic carotid artery stenosis: a 5-year prospective analysis. Circulation 2001 Jan 30;103(4):532-537.

41.   Roffi M, Robbins MA, Mukherjee D, Bhatt DL, Bajzer C, Yadav JS. Carotid stenting with emboli protection device. Images in cardiovascular medicine. Kardiovaskulaere Medizin 2001 Dec;4:347-348.

42.  Ouriel K, Hertzer NR, Beven EG, O'Hara PJ, Krajewski LP, Clair DG, Greenberg RK, Sarac TP, Olin JW, Yadav JS. Preprocedural risk stratification: identifying an appropriate population for carotid stenting. Journal of Vascular Surgery 2001 Apr;33(4):728-732.

43.  Mukherjee D, Bhatt DL, Robbins M, Roffi M, Cho L, Reginelli J, Bajzer C, Navarro F, Yadav JS. Renal artery end-diastolic velocity and renal artery resistance index as predictors of outcome after renal stenting. American Journal of Cardiology 2001 Nov 1;88(9):1064-1066.

44.  Mukherjee D, Kalahasti V, Roffi M, Bhatt DL, Kapadia SR, Bajzer C, Reginelli J, Ziada KM, Hughes K, Yadav JS. Self-expanding stents for carotid interventions: comparison of nitinol versus stainless-steel stents. Journal of Invasive Cardiology 2001 Nov;13(11):732-735.

45.  Mukherjee D, Chew DP, Robbins M, Yadav JS, Raymond RE, Moliterno DJ. Clinical application of procedural platelet, monitoring during percutaneous coronary intervention among patients at increased bleeding risk. Journal of Thrombosis and Thrombolysis 2001 Apr;11(2):151-154.

46.  Mukherjee D, Roffi M, Kapadia SR, Bhatt DL, Bajzer C, Ziada KM, Kalahasti V, Hughes K, Yadav JS. Percutaneous intervention for symptomatic vertebral artery stenosis using coronary stents. Journal of Invasive Cardiology 2001 May;13(5):363-366.

47.  Mukherjee D, Yadav JS. Update on peripheral vascular diseases: from smoking cessation to stenting. Cleveland Clinic Journal of Medicine 2001 Aug;68(8):723-733.

48.  Mukherjee D, Yadav JS. Carotid angioplasty and stenting in high-risk patients. Carotid Intervention 2001 Jan;3(1):13-15.

49.  Mukherjee D, Roffi M, Bajzer C, Yadav JS. Endovascular treatment of carotid artery aneurysms with covered stents. Circulation 2001 Dec 11;104(24):2995.

50.  Mukherjee D, Yadav JS. Effect of contralateral occlusion on long-term efficacy of endarterectomy in the Asymptomatic Carotid Atherosclerosis Study (ACAS). Stroke 2001 Jun;32(6):1443-1448.

51.   Kapadia SR, Bajzer CT, Ziada KM, Bhatt DL, Wazni OM, Silver MJ, Beven EG, Ouriel K, Yadav JS. Initial experience of platelet glycoprotein IIb/IIIa inhibition with abciximab during carotid stenting: a safe and effective adjunctive therapy. Stroke 2001 Oct;32(10):2328-2332.

52.  Grube E, Gerckens U, Yeung AC, Rowold S, Kirchhof N, Sedgewick J, Yadav JS, Stertzer S. Prevention of distal embolization during coronary angioplasty in saphenous vein grafts and native vessels using porous filter protection. Circulation 2001 Nov 13;104(20):2436-2441.

53.  Bhatt DL, Kapadia SR, Bajzer CT, Chew DP, Ziada KM, Mukherjee D, Roffi M, Topol EJ, Yadav JS. Dual antiplatelet therapy with clopidogrel and aspirin after carotid artery stenting. Journal of Invasive Cardiology 2001 Dec;13(12):767-771.

54.  Yadav JS. A review of current carotid artery stent trials. Endovascular Today 2002 Sep-Oct;1(10):36-37.

55.   Mukherjee D, Mahaffey KW, Moliterno DJ, Harrington RA, Yadav JS, Pieper KS, Gallup D, Dyke C, Roe MT, Berdan L, Lauer MS, Manttari M, White HD, Califf RM, Topol EJ. Promise of combined low-molecular-weight heparin and platelet glycoprotein IIb/IIIa inhibition: results from Platelet IIb/IIIa Antagonist for the Reduction of Acute coronary syndrome events in a Global Organization Network B (PARAGON B). American Heart Journal 2002 Dec;144(6):995-1002.

56.  Mukherjee D, Yadav JS. Percutaneous treatment for carotid stenosis. Cardiology Clinics 2002 Nov;20(4):589-597.

57.   Mukherjee D, Roffi M, Yadav JS. Endovascular treatment of carotid artery aneurysms with stent grafts. Journal of Invasive Cardiology 2002 May;14(5):269-272.

58.  Mukherjee D, Yadav JS. Carotid artery intimal-medial thickness: indicator of atherosclerotic burden and response to risk factor modification. American Heart Journal 2002 Nov;144(5):753-759.

59.  Cho L, Yadav JS. Embolization in atherosclerosis. Neuroimaging Clinics of North America 2002 Aug;12(3):365-372.

60.  Chan AW, Bhatt DL, Wilkoff BL, Roffi M, Mukherjee D, Gray BH, Baizer CT, Yadav JS. Percutaneous treatment for pacemaker-associated superior vena cava syndrome. Pacing and Clinical Electrophysiology 2002 Nov;25(11):1628-1633.

61.   Yadav JS. Angioplasty and beyond. Advance for Imaging & Radiation Therapy Professionals 2003 Mar 24;16(7):26-30.

62.  Yadav JS. Five questions. The inventor of the AngioGuard device discusses the state of innovation and technology in medicine today. Endovascular Today 2003 Apr;2(4):74.

63.  Yadav JS, Ziada KM, Almany S, Davis TP, Castaneda F. Comparison of the QuickSeal Femoral Arterial Closure System with manual compression following diagnostic and interventional catheterization procedures. American Journal of Cardiology 2003 Jun 15;91(12):1463-1466.

64.  Yadav JS. Protecting the brain: how do we measure success? Journal of the American College of Cardiology 2003 Sep;42(6):1014-1016.

65.  Yadav JS. Overview of carotid and cerebrovascular disease. Endovascular Today 2003 Nov-Dec;2(10)

66.  Roffi M, Cho L, Krieger D, Calabrese LH, Ouriel K, Yadav JS, Bajzer CT. Takayasu arteritis. Cardiology in Review 2003 Jan-Feb;11(1):3.

67.  Ouriel K, Yadav JS. The role of stents in patients with carotid disease. Reviews in Cardiovascular Medicine 2003 Spring;4(2):61-67.

68.  Moore J, Yadav JS. SAPPHIRE: Carotid stenting with emboli protection reduced risk. Carotid stenting with emboli protection was better than surgery for patients with comorbid conditions. Today in Cardiology 2003 May 13;29.

69.  Cura FA, Kapadia SR, L'Allier PL, Ziada KM, Mukherjee D, Wolski KE, Yadav JS, Brener SJ, Whitlow PL, Topol EJ, Ellis SG. Effect of uncoated stenting versus balloon angioplasty alone of long coronary (>20 mm) versus shorter narrowings on one-year event-free survival. American Journal of Cardiology 2003 Mar 1;91(5):587-590.

70.  Cho L, Roffi M, Mukherjee D, Bhatt DL, Bajzer C, Yadav JS. Superficial femoral artery occlusion: nitinol stents achieve better flow and reduce the need for medications than balloon angioplasty alone. Journal of Invasive Cardiology 2003 Apr;15(4):198-200.

71.   Cho L, Chew DP, Moliterno DJ, Roffi M, Ellis SG, Franco I, Bajzer C, Bhatt DL, Dorosti K, Simpfendorder C, Tuzcu M, Yadav JS, Brener S, Raymond R, Whitlow P, Topol EJ, Lincoff AM. Safe and efficacious use of bivalirudin for percutaneous coronary intervention with adjunctive platelet glycoprotein IIb/IIIa receptor inhibition. American Journal of Cardiology 2003 Mar 15;91(6):742-743.

72.   Chan AW, Roffi M, Mukherjee D, Bajzer CT, Abou-Chebl A, Ciezki J, Bhatt DL, Ghaffari S, Yadav JS. Carotid brachytherapy for in-stent restenosis. Catheterization and Cardiovascular Interventions 2003 Jan;58(1):86-92.

73.   Yadav JS. Carotid stenting in high-risk patients: design and rationale of the SAPPHIRE trial. Cleveland Clinic Journal of Medicine 2004 Jan;71 Suppl 1:S45-S46.

74.  Tamberella MR, Yadav JS, Bajzer CT, Bhatt DL, Abou-Chebl A. Cutting balloon angioplasty to treat carotid in-stent restenosis. Journal of Invasive Cardiology 2004 Mar;16(3):133-135.

75.   Sachar R, Yadav JS, Roffi M, Cho L, Reginelli JP, Abou-Chebl A, Bhatt DL, Bajzer CT. Severe bilateral carotid stenosis; The impact of ipsilateral stenting on Doppler-defined contralateral stenosis. Journal of the American College of Cardiology 2004 Apr 21;43(8):1358-1362.

76.  Ouriel K, Yadav J, Green RM. Standards of practice: carotid angioplasty and stenting. Journal of Vascular Surgery 2004 Apr;39(4):916-917.

77.   Ohki T, Stern D, Allen M, Yadav J. Wireless pressure sensing of aneurysms. Endovascular Today 2004 Apr;3(4):47-52.

78.  Kapadia SR, Yadav JS. Carotid and peripheral intervention. Journal of Invasive Cardiology 2004 Jul;16(7 Suppl):50S-53S.

79.  Haery C, Exaire JE, Bhatt DL, Yadav JS, Franco I, Ellis SG. Use of PercuSurge GuardWire in native coronary arteries during acute myocardial infarction. Journal of Invasive Cardiology 2004 Mar;16(3):152-154.

80.  Chen MS, Bhatt DL, Mukherjee D, Chan AW, Roffi M, Kapadia SR, Ziada KM, Chew DP, Bajzer CT, Yadav JS. Feasibility of simultaneous bilateral carotid artery stenting. Catheterization and Cardiovascular Interventions 2004 Apr;61(4):437-442.

81.   Casserly IP. Sachar R. Bajzer C. Yadav JS. Utility of IVUS-guided transaccess catheter in the treatment of long chronic total occlusion of the superficial femoral artery. Catheterization & Cardiovascular Interventions. 62(2):237-43, 2004 Jun.

82.  Chan AW, Yadav JS, Krieger D, Abou-Chebl A. Endovascular repair of carotid artery aneurysm with Jostent covered stent: Initial experience and one-year result. Catheterization and Cardiovascular Interventions 2004 Sep;63(1):15-20.

83.  Aronow HD, Yadav JS. Embolic protection for carotid artery stenting--a 'no brainer'. Acta Chirurgica Belgica 2004 Feb;104(1):65-70.

84.  Abou-Chebl A, Yadav JS, Reginelli JP, Bajzer C, Bhatt D, Krieger DW. Intracranial hemorrhage and hyperperfusion syndrome following carotid artery stenting; Risk factors, prevention, and treatment. Journal of the American College of Cardiology 2004 May 5;43(9):1596-1601.

85.  Yadav JS, Wholey MH, Kuntz RE, Fayad P, Katzen BT, Mishkel GJ, Bajwa TK, Whitlow P, Strickman NE, Jaff MR, Popma JJ, Snead DB, Cutlip DE, Firth BG, Ouriel K, for the Stenting and Angioplasty with Protection in Patients at High Risk for Endarterectomy Investigators.  Protected carotid- artery stenting versus endarterectomy in high-risk patients.  New England Journal of Medicine 2004 Oct 7;351(15):1493-1501..

86.  Saw J. Gurm HS. Fathi RB. Bhatt DL. Abou-Chebl A. Bajzer C. Yadav JS. Effect of chronic kidney disease on outcomes after carotid artery stenting.  American Journal of Cardiology. 94(8):1093-6, 2004 Oct 15.

87.  Exaire JE. Brener SJ. Ellis SG. Yadav JS. Bhatt DL. GuardWire emboli protection device is associated with improved myocardial perfusion grade in saphenous vein graft intervention. American Heart Journal. 148(6):1003-6, 2004 Dec.

88.  Yadav, JS.  Embolic protection devices: methods, techniques, and data.  Techniques in Vascular & Interventional Radiology 7(4):190-3, 2004 Dec.

89.  Cho L, Roffi M, Mukherjee D, Bhatt DL, Bajzer C, Yadav JS. Superficial femoral artery occlusion: nitinol stents achieve flow and reduce the need for medications better than balloon angioplasty alone. J Invasive Cardiol. 2004 Jan;16 Suppl A:20A-22A.

90.  Ouriel K, Wholey, MH, Fayad P, Katzen BT, Whitlow P, Feentzko M, Kuntz RE, Wechsler L, Hopkins N, Satler L, Mishkel D., Yadav JS.  Feasibility trial of carotid stenting with and without embolus protection device. Journal of Endovascular Therapy 12(5):525-37, 2005 Oct.

91.   Edgell, R. Abou-Chebl A, Yadav J, Endovascular Management of Spontaneous Carotid Artery Dissection.  J Vasc Surg, 42(5):854-60;discussion 860, 2005 Nov.

92.  Abou-Chebl A., Bashir Q, Yadav J.  Drug-Eluting Stents for the Treatment of Intracranial Atherosclerosis: Initial Experience and Midterm Angiographic Follow-up.  Stroke 36(12); e165-8, 2005 Dec.

93.  Gurm HS, Fathi R, Kapadia SR, Abou-Chebl A, Vivek DP, Bajzer C, Yadav JS.  Impact of body mass index on outcome in patients undergoing carotid stenting.  American Journal of Cardiology 96(12);1743-5; 2005 Dec 15.

94.  Yen MH. Lee DS. Kapadia S. Sachar R. Bhatt DL. Bajzer CT. Yadav JS. Symptomatic patients have similar outcomes compared with asymptomatic patients after carotid artery stenting with emboli protection. American Journal of Cardiology. 95(2):297-300, 2005 Jan 15.

95.  Chan AW, Yadav JS, Bhatt DL, Bajzer CT, Gum PA, Roffi M, Cho L, Agah R, Topol EJ.  Comparison of the safety and efficacy of emboli prevention devices versus platelet glycoprotein IIb/IIIa inhibition during carotid stenting.  American Journal of Cardiology 2005 Mar 15; 95:791-795.

96.  Gurm HS, Rajagopal V, Fathi R, Vivekanathan D, Yadav JS, Bhatt DL, Ellis SG, Lincoff AM, Topol EJ.  Effectiveness and safety of bivalirudin during percutaneous coronary intervention in a single medical center.  American Journal of Cardiology 2005 Mar 15; 95:716-721.

97.  Ziada KM. Yadav JS. Mukherjee D. Lauer MS. Bhatt DL. Kapadia S. Roffi M. Vora N. Tiong I. Bajzer C. Comparison of results of carotid stenting followed by open heart surgery versus combined carotid endarterectomy and open heart surgery (coronary bypass with or without another procedure). American Journal of Cardiology.96(4):519-23, 2005 Aug 15.

98.  Aronow, HD, Shishehbor M, Davis DA, Katzan IL, Bhatt DL, Bajzer CT, Abou-Chebl A, Derk KW, Whitlow, PL, Yadav JS. Leukocyte count predicts microembolic Doppler signals during carotid stenting: a link between imflammation and embolization.  Stroke  36(9):1910-4, 2005 Sep.

99.  Abou-Chebl A, Bajzer CT, Krieger DW, Furlan AJ, Yadav JS.  Multi-modal Therapy for the Treatment of Severe Ischemic Stroke Combining GPIIb/IIIa Antagonists and Angioplasty after Failure of Thombolysis.  Stroke 36(10):2286-8, 2005 Oct.

100.    Casserly I, Abou-Chebl A, Fathi R, Lee D, Saw J, Exaire J, Kapadia S, Bajzer C, Yadav J.  Slow-Flow Phenomenon During Carotid Artery Intervention With Embolic Protection  Devices: Predictors and Clinical Outcome. JACC, 46(8):1466-72, 2005 Oct 18.

101.         J Edurado Sousa, Marco A Costa, E Murat Tuzcu, Jay S Yadav, Stephen Ellis New Frontiers in Interventional Cardiology. Circulation 2005 Feb 8;111(5):671-81.

102.         Abou-Chebl A, Krieger DW, Bajzer CT, Yadav JS. Intracranial angioplasty and stenting in the awake patient.  J Neuroimaging. 2006 Jul;16(3):216-23. doi: 10.1111/j.1552-6569.2006.00043.x

103.         Gupta R, Abou-Chebl A, Bajzer C, H. Schumacher C, Yadav J.  Rate, Predictors and Consequences of Hemodynamic Depression after Carotid Artery Stenting.  JACC, 47;1538-1543, 2006 April 18.

104.         Yadav J.  New Insights Into Improving Acute and Long-Term Outcome of Carotid Stenting. JACC  2006 Jun 20;47(12):2397-8.

105.         Roffi M, Yadav JS.  Carotid Stenting.  Circulation 2006 Jul 4; 114(1):e1-4.

106.         Chaturvedi S, Yadav JS. The role of antiplatelet therapy in carotid stenting for ischemic stroke prevention. Stroke. 2006 Jun;37(6):1572-7. doi: 10.1161/01.STR.0000221298.43117.be. Epub 2006 Apr 20.

107.         Rajagopal V, Yadav JS. Carotid stenting: the preferred management for carotid atherosclerosis? Indian Heart J. 2006 Mar-Apr;58(2):102-7.

108.         Abou-Chebl A, Reginelli J, Bajzer CT, Yadav JS. Intensive treatment of hypertension decreases the risk of hyperperfusion and intracerebral hemorrhage following carotid artery stenting. Catheter Cardiovasc Interv. 2007 Apr 1;69(5):690-6. doi: 10.1002/ccd.20693.

109.         Fairman R, Gray WA, Scicli AP, Wilburn O, Verta P, Atkinson R, Yadav JS, Wholey M, Hopkins LN, Raabe R, Barnwell S, Green R; CAPTURE Trial Collaborators. The CAPTURE registry: analysis of strokes resulting from carotid artery stenting in the post approval setting: timing, location, severity, and type. Ann Surg. 2007 Oct;246(4):551-6; discussion 556-8. doi: 10.1097/SLA.0b013e3181567a39

110.           Gray WA, Yadav JS, Verta P, Scicli A, Fairman R, Wholey M, Hopkins LN, Atkinson R, Raabe R, Barnwell S, Green R. The CAPTURE registry: results of carotid stenting with embolic protection in the post approval setting. Catheter Cardiovasc Interv. 2007 Feb 15;69(3):341-8. doi: 10.1002/ccd.21050.

111. Gray WA, Yadav JS, Verta P, Scicli A, Fairman R, Wholey M, Hopkins LN, Atkinson R, Raabe R, Barnwell S, Green R; CAPTURE Trial Collaborators. The CAPTURE registry: predictors of outcomes in carotid artery stenting with embolic protection for high surgical risk patients in the early post-approval setting. Catheter Cardiovasc Interv. 2007 Dec 1;70(7):1025-33. doi: 10.1002/ccd.21359.

112.           Kashyap VS, Sepulveda RN, Bena JF, Nally JV, Poggio ED, Greenberg RK, Yadav JS, Ouriel K. The management of renal artery atherosclerosis for renal salvage: does stenting help? J Vasc Surg. 2007 Jan;45(1):101-8; discussion 108-9. doi: 10.1016/j.jvs.2006.08.068.

113.           Rajagopal V, Yadav JS. Management of carotid artery disease in the high-risk patient with emphasis on the SAPPHIRE study. Curr Cardiol Rep. 2007 Mar;9(1):20-4. doi: 10.1007/s11886-007-0005-x.

114.           Gurm HS, Yadav JS, Fayad P, et al. for the SAPPHIRE Investigators. Long-Term Results of Carotid Stenting versus Endarterectomy in High-Risk Patients. N Engl J Med 2008; 358:1572-1579

115.           Helton TJ, Bavry AA, Rajagopal V, Anderson RD, Yadav JS, Bhatt DL. The optimal treatment of carotid atherosclerosis: a 2008 update and literature review. Postgrad Med. 2008 Sep;120(3):103-12. doi: 10.3810/pgm.2008.09.1911.

116.           Mazighi M, Yadav JS, Abou-Chebl A. Durability of endovascular therapy for symptomatic intracranial atherosclerosis. Stroke. 2008 Jun;39(6):1766-9. doi: 10.1161/STROKEAHA.107.500587. Epub 2008 Apr 17.

117. Yadav JS. Assessing carotid revascularization should we abandon the neurological examination? JACC Cardiovasc Interv. 2008 Oct;1(5):578-9. doi: 10.1016/j.jcin.2008.08.016.

118.           Abou-Chebl A, Vora N, Yadav JS Safety of angioplasty and stenting without thrombolysis for the treatment of early ischemic stroke. J Neuroimaging. 2009 Apr;19(2):139-43. doi: 10.1111/j.1552-6569.2008.00267.x. Epub 2008 Sep 29.

119.           Yadav JS, Abou-Chebl A. Intracranial angioplasty and stenting. J Interv Cardiol. 2009 Feb;22(1):9-15. doi: 10.1111/j.1540-8183.2008.00415.x.

120.         Adamson PB, Abraham WT, Bourge RC, Stevenson LW, Yadav J. CardioMEMS Heart Sensor Allows Monitoring of Pressures to Improve Outcomes in NYHA Class III Heart Failure Patients (CHAMPION) Trial: Impact of Hemodynamic Guided Care on Patients With Preserved Ejection Fraction. J Card Fail. 2010 Nov;17(11):913.

121.           Roffi M, Sievert H, Gray WA, White CJ, Torsello G, Cao P, Reimers B, Mathias K, Setacci C, Schönholz C, Clair DG, Schillinger M, Grunwald I, Bosiers M, Abou-Chebl A, Moussa ID, Mudra H, Iyer SS, Scheinert D, Yadav JS, van Sambeek MR, Holmes DR, Cremonesi A. Carotid artery stenting versus surgery: adequate comparisons? Lancet Neurol. 2010 Apr;9(4):339-41; author reply 341-2. doi: 10.1016/S1474-4422(10)70027-2. Epub

122.         Stolker JM, Mahoney EM, Safley DM, Pomposelli FB Jr, Yadav JS, Cohen DJ; SAPPHIRE Investigators. Health-related quality of life following carotid stenting versus endarterectomy: results from the SAPPHIRE (Stenting and Angioplasty with Protection in Patients at HIgh Risk for Endarterectomy) trial. JACC Cardiovasc Interv. 2010 May;3(5):515-23. doi: 10.1016/j.jcin.2010.02.009.

123.         Yadav JS. Functional occlusions of the carotid artery (string signs): to treat or not to treat? JACC Cardiovasc Interv. 2010 Mar;3(3):305-6. doi: 10.1016/j.jcin.2010.01.005.

124.         Adamson PB, Abraham WT, Aaron M, Aranda JM Jr, Bourge RC, Smith A, Stevenson LW, Bauman JG, Yadav JS. CHAMPION trial rationale and design: the long-term safety and clinical efficacy of a wireless pulmonary artery pressure monitoring system. J Card Fail. 2011 Jan;17(1):3-10.

125.         William T Abraham, Philip B Adamson, Robert C Bourge, Mark F Aaron, Maria Rosa Costanzo, Lynne W Stevenson, Warren Strickland, Suresh Neelagaru, Nirav Raval, Steven Krueger, Stanislav Weiner, David Shavelle, Bradley Jeffries, Jay S Yadav, for the CHAMPION Trial Study Group. Wireless Pulmonary Artery Haemodynamic Monitoring In Chronic Heart Failure: A Randomised Controlled Trial. Lancet 2011; 377: 658-66.

126.         Mahoney EM, Greenberg D, Lavelle TA, Natarajan A, Berezin R, Ishak KJ, Caro JJ, Yadav JS, Gray WA, Wholey MH, Cohen DJ. Costs and cost-effectiveness of carotid stenting versus endarterectomy for patients at increased surgical risk: results from the SAPPHIRE trial. Catheter Cardiovasc Interv. 2011 Mar 1;77(4):463-72. doi: 10.1002/ccd.22869.

127.           Abraham T, Stough WG, Pina IL, Linde C, Borer JS, DeFerrari GM, Mehran R, Stein KM, Vincent A, Yadav JS, Anker SD and Zannad F. Nat Rev Cardiol 12 August 2014, 11: 576-85; doi:10.1038/nrcardio.2014.114

128.         Saw J, Bajzer C, Casserly I, Exaire J, Haery C, Sahar R, Lee D, Abou-Chebl A, Yadav JS.  Evaluating the Optimal Activated Clotting Time During Carotid Stenting.  American Journal of Cardiology.  (In Press).

129.         Wood TA, Abbott DJ, Yadav JS.  Percutaneous intervention for subclavian artery stenosis in patients with internal mammary artery grafts: acute and long-term results.  Journal of Interventional Cardiology (Accepted).

130.         Gurm HS, Yadav JS.  A new look at treatment of carotid artery disease in high-risk patients.  Cardiology Review.  (Accepted).

131.           Yadav JS.  Carotid artery stenting in asymptomatic patients at high risk for carotid endarterectomy  Endovascular Today.  (Accepted).

132.         Rajagopal V, Yadav JS.  Carotid Stenting: Minimizing Complications and Optimizing Benefits.  Journal of Interventional Cardiology, Special Supplement for i2 Summit 2006.  (Accepted).

Books

1.      Mendelsohn FO, Mahaffey KW, Bajzer C, Yadav JS.  Carotid Artery Disease: Remedica Books, London, 2000.

2.     Casserly IP, Sachar R, Yadav JS.  Manual of Peripheral Vascular Intervention: Lippincott Williams & Wilkins, Philadelphia, First Edition 2005; Second Edition 2010.

External links

TBD