User:Queen'smed22/sandbox
“ANP increases glomerular filtration rate and glomerular permeability. [1] ANP directly dilates the afferent arteriole and counteracts the norepinephrine induced vasoconstriction of the afferent arteriole. [2] Some studies suggest that ANP also constricts the efferent arteriole, but this is not a unanimous finding. [2] ANP inhibits the effect of Angiotensin II on the mesangial cells, thereby relaxing them. [2] ANP increases the radius and number of glomerular pores, thereby increasing glomerular permeability." [1]
“The medullary collecting duct is the main site of ANP regulation of sodium excretion. [1] ANP effects sodium channels at both the apical and basolateral sides. [1] ANP inhibits ENaC on the apical side and the Sodium Potassium ATPase pump on the basolateral side in a cGMP PKG dependent manner resulting in less sodium re-absorption and more sodium excretion." [2]
- ^ a b c d Theilig, Franziska; Wu, Qingyu (2015-05-15). "ANP-induced signaling cascade and its implications in renal pathophysiology". American Journal of Physiology-Renal Physiology. 308 (10): F1047–F1055. doi:10.1152/ajprenal.00164.2014. ISSN 1931-857X. PMC 4436998. PMID 25651559.
{{cite journal}}: CS1 maint: PMC format (link) - ^ a b c d Fu, Shihui; Ping, Ping; Wang, Fengqi; Luo, Leiming (2018-01-12). "Synthesis, secretion, function, metabolism and application of natriuretic peptides in heart failure". Journal of Biological Engineering. 12 (1). doi:10.1186/s13036-017-0093-0. ISSN 1754-1611. PMC 5766980. PMID 29344085.
{{cite journal}}: CS1 maint: PMC format (link) CS1 maint: unflagged free DOI (link)
Comments
[edit]Thanks for sharing your improvements.
- References go immediately after the punctuation like this.1 No spaces between the period and punctuation.
- In the actual WP article, please don't use quotation marks.
- Can you add some wikilinks here?
Great work so far! There are more comments on the article talk page. JenOttawa (talk) 17:59, 6 November 2018 (UTC)