User talk:Yuyanchen97

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Hello, Yuyanchen97, and welcome to Wikipedia! My name is Ian and I work with the Wiki Education Foundation; I help support students who are editing as part of a class assignment.

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If you have any questions, please don't hesitate to contact me on my talk page. Ian (Wiki Ed) (talk) 12:50, 11 September 2017 (UTC)

Critique of Wikipedia Page on Peptidoglycan

The Start-Class rated Wikipedia page on peptidoglycan leads readers to browse the topic through four different headings: structure, synthesis, inhibition, and similarity to pseudopeptidoglycan. Overall, the page provides a clear overview on the chemistry behind peptidoglycan structure and its synthesis process through a felicitous use of hyperlinks, neutral viewpoint, and reliable references from academic presses. However, the imbalanced coverage for equally important headings, missing relevant sections for information that is introduced in the lead, and lack of images to augment the understanding of chemical reactions suggest areas for improvement. The page’s extensive coverage of peptidoglycan structure and synthesis process compared to the brief inhibition section is unjustified considering the importance of understanding antibiotic mechanisms for disease treatments. In addition to penicillin and lysozyme, β-lactam antibiotics such as cephalosporins and carbapenems also inhibit peptidoglycan synthesis. The page should elaborate on how they inhibit transpeptidation reactions and make connections with the different peptidoglycan synthesis process in cocci and non-spherical bacteria during binary fission. Pivotal aspects, such as the function of peptidoglycan and the differences between gram positive and negative bacterial peptidoglycan, that are touched on in the lead have the potential to develop into new headings. Peptidoglycan’s usage in preventing bacteria from undergoing osmotic lysis in a hypotonic environment and its inability to prevent antibiotics from entering the bacteria should be elaborated in a new heading for peptidoglycan functions. Moreover, bacterial detection through the different proteins embedded in gram positive and negative bacteria’s peptidoglycan is also an important aspect .--Yuyanchen97 (talk) 19:53, 17 September 2017 (UTC)