WASF3

WASF3
Identifiers
Aliases	WASF3, Brush-1, SCAR3, WAVE3, WAS protein family member 3, WASP family member 3
External IDs	OMIM: 605068; MGI: 2658986; HomoloGene: 68527; GeneCards: WASF3; OMA:WASF3 - orthologs
Gene location (Human)
Chr.	Chromosome 13 (human)
End	26,688,948 bp
Gene location (Mouse)
Chr.	Chromosome 5 (mouse)
End	146,410,425 bp
RNA expression pattern
	Top expressed in
	Pars compacta; ; pars reticulata; ; paraflocculus of cerebellum; ; lateral nuclear group of thalamus; ; orbitofrontal cortex; ; cerebellar vermis; ; postcentral gyrus; ; external globus pallidus; ; Brodmann area 46; ; dorsal motor nucleus of vagus nerve;
	Top expressed in
	ventral tegmental area; ; neural layer of retina; ; lobe of cerebellum; ; cerebellar vermis; ; dorsomedial hypothalamic nucleus; ; mammillary body; ; globus pallidus; ; lateral hypothalamus; ; lateral septal nucleus; ; deep cerebellar nuclei;
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	actin binding;
Cellular component	cytoplasm; extracellular exosome; cytoskeleton; lamellipodium; postsynapse; glutamatergic synapse;
Biological process	positive regulation of myelination; oligodendrocyte development; actin filament polymerization; cytoskeleton organization; actin cytoskeleton organization; lamellipodium assembly; regulation of cell shape; protein-containing complex assembly; modification of postsynaptic actin cytoskeleton;
	Sources:Amigo / QuickGO
Orthologs
	10810
	245880
	ENSG00000132970
	ENSMUSG00000029636
	Q9UPY6; Q5T8P4
	Q8VHI6
	NM_001291965; NM_006646
	NM_145155
	NP_001278894; NP_006637; NP_006637.2
	NP_660137
	Wikidata
View/Edit Human	View/Edit Mouse

Wiskott-Aldrich syndrome protein family member 3 is a protein that in humans is encoded by the WASF3 gene.^[5]^[6]

Template:PBB Summary

References

^ ^a ^b ^c GRCh38: Ensembl release 89: ENSG00000132970 – Ensembl, May 2017
^ ^a ^b ^c GRCm38: Ensembl release 89: ENSMUSG00000029636 – Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ Suetsugu S, Miki H, Takenawa T (Jul 1999). "Identification of two human WAVE/SCAR homologues as general actin regulatory molecules which associate with the Arp2/3 complex". Biochem Biophys Res Commun. 260 (1): 296–302. doi:10.1006/bbrc.1999.0894. PMID 10381382.
^ "Entrez Gene: WASF3 WAS protein family, member 3".

References

Further reading