Born in Charlotte, North Carolina, Harrison had a Billboard #1 record in 1959 with the song "Kansas City". The song was written in 1952 and was one of the first credited collaborations by the team of Jerry Leiber and Mike Stoller. It sold over one million copies, and was awarded a gold disc. Harrison recorded "Kansas City" for the Harlem based entrepreneur Bobby Robinson, who released it on his Fury record label.
At the height of the song's success, Robinson got sued by Savoy Records who informed them that the release of the record in March 1959 violated a contract Harrison had with that label that was to expire in August 1959. The litigation, which lasted until September 1959, abruptly prevented Robinson from issuing follow-ups to "Kansas City" while Harrison was a star.
Meanwhile, Harrison continued to perform and record but it would be another ten years before he again cracked the Billboard Top 40 when he released the self-penned "Let's Work Together (Part 1)" that went to #32 in early 1970 on the Billboard Hot 100. The 1970 hit version was released as a single on Sue Records (Sue 11) and was backed with "Let's Work Together (Part 2)". The song also was released in a 5 minute 19 second version on the Sue Records album SSLP-8801 Let's Work Together. The song was originally released by Harrison in 1962 with different lyrics as "Let's Stick Together" on Fury 1059 and Fury 1063.
"Let's Work Together" was later a hit for Canned Heat, and, again as "Let's Stick Together", for Bryan Ferry. It was also recorded by country rock band the Kentucky Headhunters for the soundtrack to the movie Harley Davidson and the Marlboro Man.
In 1970, Harrison had some success with "My Heart Is Yours", and he toured for many years with a band known as 'Wilbert Harrison and the Roamers', and as a solo act.
In 2001, his recording of "Kansas City" was given a Grammy Hall of Fame Award, and has also been named as one of the Rock and Roll Hall of Fame's 500 Songs that Shaped Rock and Roll. Harrison was inducted into the North Carolina Music Hall of Fame in 2009.
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- "2009 Inductees". North Carolina Music Hall of Fame. Retrieved September 10, 2012.