Y-27632

Y-27632
Names
	IUPAC name (1R,4r)-4-((R)-1-aminoethyl)-N-(pyridin-4-yl)cyclohexanecarboxamide
Identifiers
CAS Number	146986-50-7 ;
3D model (JSmol)	Interactive image;
ChEBI	CHEBI:75393 ;
ChEMBL	ChEMBL2218937 ;
ChemSpider	20016532 ;
DrugBank	DB08756 ;
ECHA InfoCard	100.149.247
IUPHAR/BPS	5290;
PubChem CID	448042;
CompTox Dashboard (EPA)	DTXSID7043740 ;
	InChI InChI=1S/C14H21N3O/c1-10(15)11-2-4-12(5-3-11)14(18)17-13-6-8-16-9-7-13/h6-12H,2-5,15H2,1H3,(H,16,17,18)/t10-,11-,12-/m1/s1 Key: IYOZTVGMEWJPKR-IJLUTSLNSA-N ; InChI=1/C14H21N3O/c1-10(15)11-2-4-12(5-3-11)14(18)17-13-6-8-16-9-7-13/h6-12H,2-5,15H2,1H3,(H,16,17,18)/t10-,11-,12-/m1/s1 Key: IYOZTVGMEWJPKR-IJLUTSLNBP;
	SMILES O=C([C@H]1CC[C@@]([C@H](N)C)([H])CC1)NC2=CC=NC=C2;
Properties
Chemical formula	C14H21N3O
Molar mass	247.342 g·mol−1
	Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa). verify (what is ?) Infobox references

Y-27632 is a biochemical tool used in the study of the rho-associated protein kinase (ROCK) signaling pathways.^[1] Y-27632 selectively inhibits p160ROCK.^[2]

References

^ Uehata, Masayoshi (1999). "Y-27632. Selective probe of ROCK/Rho-kinase". Jikken Igaku. 17 (7): 850–855.
^ Uehata, M; Ishizaki, T; Satoh, H; Ono, T; Kawahara, T; Morishita, T; Tamakawa, H; Yamagami, K; et al. (1997). "Calcium sensitization of smooth muscle mediated by a Rho-associated protein kinase in hypertension". Nature. 389 (6654): 990–4. doi:10.1038/40187. PMID 9353125.

This article about an organic compound is a stub. You can help Wikipedia by expanding it.

[1] Uehata, Masayoshi (1999). "Y-27632. Selective probe of ROCK/Rho-kinase". Jikken Igaku. 17 (7): 850–855.

[2] Uehata, M; Ishizaki, T; Satoh, H; Ono, T; Kawahara, T; Morishita, T; Tamakawa, H; Yamagami, K; et al. (1997). "Calcium sensitization of smooth muscle mediated by a Rho-associated protein kinase in hypertension". Nature. 389 (6654): 990–4. doi:10.1038/40187. PMID 9353125.

[1]

[2]