Homoaconitic acid
 cis-Homoaconitic acid
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 trans-Homoaconitic acid
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| Names | |
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| IUPAC names
(1Z)-1-Butene-1,2,4-tricarboxylic acid
(1E)-1-Butene-1,2,4-tricarboxylic acid | |
| Other names
Homo-cis-aconitate; Homo-trans-aconitate
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| Identifiers | |
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3D model (JSmol)
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| ChemSpider |
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PubChem CID
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| UNII | |
CompTox Dashboard (EPA)
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| Properties | |
| C7H8O6 | |
| Molar mass | 188.135 g·mol−1 |
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
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Homoaconitatic acid (homoaconitate) is related to aconitic acid but with one extra carbon. It is part of the α-aminoadipate pathway for lysine biosynthesis, where it is made from homocitrate by homoaconitase.[1] It is converted to homoisocitrate by homoisocitrate dehydrogenase.
See also
[edit]References
[edit]- ^ Murray Strassman and Louis N. Ceci (1966). "Enzymatic Formation of cis-Homoaconitic Acid, an Intermediate in Lysine Biosynthesis in Yeast". The Journal of Biological Chemistry. 241 (22): 5401–5407. doi:10.1016/S0021-9258(18)96444-6. PMID 5954805.
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