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'''Benign lipoblastomatosis''' is a tumor consisting of [[Fetus|fetal]]-[[Embryo|embryonal]] [[Adipocyte|adipocytes]], frequently confused with a [[liposarcoma]], affecting exclusively infants and young children, with approximately 90% of cases occurring before 3 years of age.<ref>{{cite journal |last1=Kumar |first1=A. |last2=Brierley |first2=D. |last3=Hunter |first3=K.D. |last4=Lee |first4=N. |title=Rapidly-growing buccal mass in a 6-month-old infant |journal=British Journal of Oral and Maxillofacial Surgery |date=November 2015 |volume=53 |issue=9 |pages=888–890 |doi=10.1016/j.bjoms.2015.07.006}}</ref><ref name="Andrews">James, William; Berger, Timothy; Elston, Dirk (2005). ''Andrews' Diseases of the Skin: Clinical Dermatology''. (10th ed.). Saunders. {{ISBN|0-7216-2921-0}}.</ref>{{rp|626}} The term lipoblastomatosis was first used by Vellios et al. in 1958, at which point the tumor became generally accepted as a distinctive entity.<ref>{{cite journal |last1=Vellios |first1=F |last2=Baez |first2=J |last3=Shumacker |first3=HB |title=Lipoblastomatosis: a tumor of fetal fat different from hibernoma; report of a case, with observations on the embryogenesis of human adipose tissue. |journal=[[The American journal of pathology]] |date=November 1958 |volume=34 |issue=6 |pages=1149-59 |pmid=13583102}}</ref><ref>{{cite journal |last1=Gammelgaard |first1=Niels |last2=Jørgensen |first2=Karstein |last3=Lund |first3=Claus |title=Benign Lipoblastoma in the Neck Causing Respiratory Insufficiency: |journal=[[The Laryngoscope]] |date=July 1983 |volume=93 |issue=7 |pages=935???937 |doi=10.1288/00005537-198307000-00017}}</ref> Today '''Diffuse lipoblastoma''' is the preferred term for Lipoblastomatosis.<ref>{{cite journal |last1=Robinson |first1=Philip |last2=Vanhoenacker |first2=Filip M. |title=Adipocytic Tumors |journal=Imaging of Soft Tissue Tumors |date=2017 |pages=197–241 |doi=10.1007/978-3-319-46679-8_12}}</ref><ref>{{cite journal |last1=Ahlawat |first1=Shivani |last2=M. Fayad |first2=Laura |title=Revisiting the WHO classification system of soft tissue tumours: emphasis on advanced magnetic resonance imaging sequences. Part 1 |journal=Polish Journal of Radiology |date=2020 |volume=85 |issue=1 |pages=396–408 |doi=10.5114/pjr.2020.98685}}</ref> The tumor is rare, accounting for less than 1% of all childhood [[neoplasm]],<ref name=":kamal">{{cite journal |last1=Kamal |first1=Achmad Fauzi |last2=Wiratnaya |first2=I. Gde Eka |last3=Hutagalung |first3=Errol Untung |last4=Prasetyo |first4=Marcel |last5=Kodrat |first5=Evelina |last6=Widodo |first6=Wahyu |last7=Effendi |first7=Zuhri |last8=Husodo |first8=Kurniadi |title=Lipoblastoma and Lipoblastomatosis of the Lower Leg |journal=Case Reports in Orthopedics |date=2014-09-15 |doi=10.1155/2014/582876 |url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4181785/}}</ref> and it has been found to be more common in males than females.<ref name="calobrisi">{{cite journal |last1=Calobrisi |first1=Stella D. |last2=Garland |first2=Jeffery S. |last3=Esterly |first3=Nancy B. |title=Congenital Lipoblastomatosis of the Lower Extremity in a Neonate |journal=Pediatric Dermatology |date=1998 |volume=15 |issue=3 |pages=210–213 |doi=10.1111/j.1525-1470.1998.tb01318.x}}</ref><ref name=":kamal" /> It often presents as an [[asymptomatic]] rapidly enlarging mass, occurring more often in the soft tissues of the extremities.<ref name=":kamal" /><ref name="calobrisi" />
'''Benign lipoblastomatosis''' is a tumor frequently confused with a [[liposarcoma]], affecting exclusively infants and young children, with approximately 90% occurring before 3 years of age.<ref name="Andrews">James, William; Berger, Timothy; Elston, Dirk (2005). ''Andrews' Diseases of the Skin: Clinical Dermatology''. (10th ed.). Saunders. {{ISBN|0-7216-2921-0}}.</ref>{{rp|626}}


==See also==
==See also==
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==References==
==References==
{{reflist}}
{{reflist}}

== External links ==
== External links ==
{{Medical resources
{{Medical resources

Revision as of 06:53, 15 June 2021

Benign lipoblastomatosis
Other namesEmbryonic lipoma[1]
SpecialtyDermatology

Benign lipoblastomatosis is a tumor consisting of fetal-embryonal adipocytes, frequently confused with a liposarcoma, affecting exclusively infants and young children, with approximately 90% of cases occurring before 3 years of age.[2][3]: 626  The term lipoblastomatosis was first used by Vellios et al. in 1958, at which point the tumor became generally accepted as a distinctive entity.[4][5] Today Diffuse lipoblastoma is the preferred term for Lipoblastomatosis.[6][7] The tumor is rare, accounting for less than 1% of all childhood neoplasm,[8] and it has been found to be more common in males than females.[9][8] It often presents as an asymptomatic rapidly enlarging mass, occurring more often in the soft tissues of the extremities.[8][9]

See also

References

  1. ^ Rapini, Ronald P.; Bolognia, Jean L.; Jorizzo, Joseph L. (2007). Dermatology: 2-Volume Set. St. Louis: Mosby. ISBN 1-4160-2999-0.
  2. ^ Kumar, A.; Brierley, D.; Hunter, K.D.; Lee, N. (November 2015). "Rapidly-growing buccal mass in a 6-month-old infant". British Journal of Oral and Maxillofacial Surgery. 53 (9): 888–890. doi:10.1016/j.bjoms.2015.07.006.
  3. ^ James, William; Berger, Timothy; Elston, Dirk (2005). Andrews' Diseases of the Skin: Clinical Dermatology. (10th ed.). Saunders. ISBN 0-7216-2921-0.
  4. ^ Vellios, F; Baez, J; Shumacker, HB (November 1958). "Lipoblastomatosis: a tumor of fetal fat different from hibernoma; report of a case, with observations on the embryogenesis of human adipose tissue". The American journal of pathology. 34 (6): 1149–59. PMID 13583102.
  5. ^ Gammelgaard, Niels; Jørgensen, Karstein; Lund, Claus (July 1983). "Benign Lipoblastoma in the Neck Causing Respiratory Insufficiency:". The Laryngoscope. 93 (7): 935???937. doi:10.1288/00005537-198307000-00017.
  6. ^ Robinson, Philip; Vanhoenacker, Filip M. (2017). "Adipocytic Tumors". Imaging of Soft Tissue Tumors: 197–241. doi:10.1007/978-3-319-46679-8_12.
  7. ^ Ahlawat, Shivani; M. Fayad, Laura (2020). "Revisiting the WHO classification system of soft tissue tumours: emphasis on advanced magnetic resonance imaging sequences. Part 1". Polish Journal of Radiology. 85 (1): 396–408. doi:10.5114/pjr.2020.98685.
  8. ^ a b c Kamal, Achmad Fauzi; Wiratnaya, I. Gde Eka; Hutagalung, Errol Untung; Prasetyo, Marcel; Kodrat, Evelina; Widodo, Wahyu; Effendi, Zuhri; Husodo, Kurniadi (2014-09-15). "Lipoblastoma and Lipoblastomatosis of the Lower Leg". Case Reports in Orthopedics. doi:10.1155/2014/582876.{{cite journal}}: CS1 maint: unflagged free DOI (link)
  9. ^ a b Calobrisi, Stella D.; Garland, Jeffery S.; Esterly, Nancy B. (1998). "Congenital Lipoblastomatosis of the Lower Extremity in a Neonate". Pediatric Dermatology. 15 (3): 210–213. doi:10.1111/j.1525-1470.1998.tb01318.x.