Liposarcoma
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| Liposarcoma | |
|---|---|
| Classification and external resources | |
| ICD-O: | M8850/3 |
| DiseasesDB | 31482 |
| eMedicine | derm/856 |
| MeSH | D008080 |
Liposarcoma is a malignant tumor[1] that arises in fat cells in deep soft tissue, such as that inside the thigh or in the retroperitoneum.
They are typically large bulky tumors which tend to have multiple smaller satellites extending beyond the main confines of the tumor.
Liposarcomas, like all sarcomas, are rare and may be best treated at sarcoma centers.[2]
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[edit] Symptoms
Patients usually note a deep seated mass in their soft tissue. Only when the tumor is very large do symptoms of pain or functional disturbances occur.
Retroperitoneal tumors may present themselves with signs of weight loss and emaciation and abdominal pain. These tumors may also compress the kidney or ureter leading to kidney failure.
[edit] Incidence and prevalence
Most frequent in middle-aged and older adults (age 40 and above), liposarcomas are the second most common of all soft-tissue sarcomas following malignant fibrous histiocytomas. Annually 2.5 cases occur per million population.
[edit] Prognosis
The prognosis varies depending on the site of origin, the type of cancer cell, the tumor size, the depth, and proximity to lymph nodes. Well-differentiated liposarcomas treated with surgery and radiation have a low recurrence rate (about 10%) and rarely metastasize.[3] Five year survival rates vary from 100% to 39% based on histological subtype.[3]
[edit] See also
[edit] References
- ^ Dei Tos AP (August 2000). "Liposarcoma: new entities and evolving concepts". Ann Diagn Pathol 4 (4): 252–66. doi:. PMID 10982304. http://linkinghub.elsevier.com/retrieve/pii/S1092-9134(00)74153-0.
- ^ Goldstein-Rice, E (2008). "The Importance of Treatment at a Specialty Center for Sarcomas". ESUN. http://sarcomahelp.org/learning_center/articles/sarcoma_centers.html.
- ^ a b Gebhardt, M and Buecker, PJ (2004). "Liposarcoma". ESUN. http://sarcomahelp.org/liposarcoma.html.
[edit] External links
- humpath #2495 (Pathology images)
- Information from The Doctor's Doctor website
- Liposarcoma in the Sarcoma Learning Center
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