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{{PBB|geneid=79633}}
{{protein
'''Protocadherin Fat 4''', also known as '''cadherin family member 14''' (CDHF14) or '''FAT tumor suppressor homolog 4''' (FAT4), is a [[protein]] that in humans is encoded by the ''FAT4'' [[gene]].<ref name="entrez">{{cite web | title = Entrez Gene: FAT tumor suppressor homolog 4 (Drosophila)| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=79633| accessdate = }}</ref><ref name="pmid15003449">{{cite journal | author = Höng JC, Ivanov NV, Hodor P, Xia M, Wei N, Blevins R, Gerhold D, Borodovsky M, Liu Y | title = Identification of new human cadherin genes using a combination of protein motif search and gene finding methods | journal = J. Mol. Biol. | volume = 337 | issue = 2 | pages = 307–17 | year = 2004 | month = March | pmid = 15003449 | doi = 10.1016/j.jmb.2004.01.026 | url = | issn = }}</ref>
|name=FAT tumor suppressor homolog 4 (Drosophila)

|caption=
⚫
FAT4 is associated with the [[Hippo signaling pathway]].<ref name="pmid19048595">{{cite journal |author=Qi C, Zhu YT, Hu L, Zhu YJ |title=Identification of Fat4 as a candidate tumor suppressor gene in breast cancers |journal=Int. J. Cancer |volume=124 |issue=4 |pages=793–8 |year=2009 |month=February |pmid=19048595 |pmc=2667156 |doi=10.1002/ijc.23775 |url=}}</ref>
|image=
|width=
|HGNCid=23109
|Symbol=FAT4
|AltSymbols=
|EntrezGene=79633
|OMIM=612411
|RefSeq=NM_024582
|UniProt=
|PDB=
|ECnumber=
|Chromosome=4
|Arm=q
|Band=28.1
|LocusSupplementaryData=
}}
⚫
'''FAT4''' is a [[human gene]] associated with the [[Hippo signaling pathway]].<ref name="pmid19048595">{{cite journal |author=Qi C, Zhu YT, Hu L, Zhu YJ |title=Identification of Fat4 as a candidate tumor suppressor gene in breast cancers |journal=Int. J. Cancer |volume=124 |issue=4 |pages=793–8 |year=2009 |month=February |pmid=19048595 |pmc=2667156 |doi=10.1002/ijc.23775 |url=}}</ref>


==References==
==References==
{{reflist}}
{{reflist}}


==Further reading==
⚫
{{Hippo signaling pathway}}
{{refbegin | 2}}
*{{cite journal |author=Katoh Y, Katoh M |title=Comparative integromics on FAT1, FAT2, FAT3 and FAT4. |journal=Int. J. Mol. Med. |volume=18 |issue= 3 |pages= 523-8 |year= 2006 |pmid= 16865240 |doi= }}
*{{cite journal |author=Caporaso N, Gu F, Chatterjee N, ''et al.'' |title=Genome-wide and candidate gene association study of cigarette smoking behaviors. |journal=PLoS ONE |volume=4 |issue= 2 |pages= e4653 |year= 2009 |pmid= 19247474 |doi= 10.1371/journal.pone.0004653 }}
*{{cite journal |author=Liu Y, Blackwood DH, Caesar S, ''et al.'' |title=Meta-analysis of genome-wide association data of bipolar disorder and major depressive disorder. |journal=Molecular psychiatry |volume= |issue= |pages= HASH(0x11aa390) |year= 2010 |pmid= 20351715 |doi= 10.1038/mp.2009.107 }}
*{{cite journal |author=Need AC, Attix DK, McEvoy JM, ''et al.'' |title=A genome-wide study of common SNPs and CNVs in cognitive performance in the CANTAB. |journal=Hum. Mol. Genet. |volume=18 |issue= 23 |pages= 4650-61 |year= 2009 |pmid= 19734545 |doi= 10.1093/hmg/ddp413 }}
*{{cite journal |author=Rose JE, Behm FM, Drgon T, ''et al.'' |title=Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. |journal=Mol. Med. |volume=16 |issue= 7-8 |pages= 247-53 |year= |pmid= 20379614 |doi= 10.2119/molmed.2009.00159 }}
*{{cite journal |author=Ballif BA, Villén J, Beausoleil SA, ''et al.'' |title=Phosphoproteomic analysis of the developing mouse brain. |journal=Mol. Cell Proteomics |volume=3 |issue= 11 |pages= 1093-101 |year= 2004 |pmid= 15345747 |doi= 10.1074/mcp.M400085-MCP200 }}
*{{cite journal |author=Johnson AD, Kavousi M, Smith AV, ''et al.'' |title=Genome-wide association meta-analysis for total serum bilirubin levels. |journal=Hum. Mol. Genet. |volume=18 |issue= 14 |pages= 2700-10 |year= 2009 |pmid= 19414484 |doi= 10.1093/hmg/ddp202 }}
*{{cite journal |author=Lim J, Hao T, Shaw C, ''et al.'' |title=A protein-protein interaction network for human inherited ataxias and disorders of Purkinje cell degeneration. |journal=Cell |volume=125 |issue= 4 |pages= 801-14 |year= 2006 |pmid= 16713569 |doi= 10.1016/j.cell.2006.03.032 }}
{{refend}}


⚫
{{Hippo signaling pathway}}

{{Genetics-stub}}
{{gene-4-stub}}

Revision as of 02:04, 29 November 2010

Template:PBB Protocadherin Fat 4, also known as cadherin family member 14 (CDHF14) or FAT tumor suppressor homolog 4 (FAT4), is a protein that in humans is encoded by the FAT4 gene.[1][2]

FAT4 is associated with the Hippo signaling pathway.[3]

References

  1. ^ "Entrez Gene: FAT tumor suppressor homolog 4 (Drosophila)".
  2. ^ Höng JC, Ivanov NV, Hodor P, Xia M, Wei N, Blevins R, Gerhold D, Borodovsky M, Liu Y (2004). "Identification of new human cadherin genes using a combination of protein motif search and gene finding methods". J. Mol. Biol. 337 (2): 307–17. doi:10.1016/j.jmb.2004.01.026. PMID 15003449. {{cite journal}}: Unknown parameter |month= ignored (help)CS1 maint: multiple names: authors list (link)
  3. ^ Qi C, Zhu YT, Hu L, Zhu YJ (2009). "Identification of Fat4 as a candidate tumor suppressor gene in breast cancers". Int. J. Cancer. 124 (4): 793–8. doi:10.1002/ijc.23775. PMC 2667156. PMID 19048595. {{cite journal}}: Unknown parameter |month= ignored (help)CS1 maint: multiple names: authors list (link)

Further reading

  • Katoh Y, Katoh M (2006). "Comparative integromics on FAT1, FAT2, FAT3 and FAT4". Int. J. Mol. Med. 18 (3): 523–8. PMID 16865240.
  • Caporaso N, Gu F, Chatterjee N; et al. (2009). "Genome-wide and candidate gene association study of cigarette smoking behaviors". PLoS ONE. 4 (2): e4653. doi:10.1371/journal.pone.0004653. PMID 19247474. {{cite journal}}: Explicit use of et al. in: |author= (help)CS1 maint: multiple names: authors list (link) CS1 maint: unflagged free DOI (link)
  • Liu Y, Blackwood DH, Caesar S; et al. (2010). "Meta-analysis of genome-wide association data of bipolar disorder and major depressive disorder". Molecular psychiatry: HASH(0x11aa390). doi:10.1038/mp.2009.107. PMID 20351715. {{cite journal}}: Explicit use of et al. in: |author= (help)CS1 maint: multiple names: authors list (link)
  • Need AC, Attix DK, McEvoy JM; et al. (2009). "A genome-wide study of common SNPs and CNVs in cognitive performance in the CANTAB". Hum. Mol. Genet. 18 (23): 4650–61. doi:10.1093/hmg/ddp413. PMID 19734545. {{cite journal}}: Explicit use of et al. in: |author= (help)CS1 maint: multiple names: authors list (link)
  • Rose JE, Behm FM, Drgon T; et al. "Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score". Mol. Med. 16 (7–8): 247–53. doi:10.2119/molmed.2009.00159. PMID 20379614. {{cite journal}}: Explicit use of et al. in: |author= (help)CS1 maint: multiple names: authors list (link)
  • Ballif BA, Villén J, Beausoleil SA; et al. (2004). "Phosphoproteomic analysis of the developing mouse brain". Mol. Cell Proteomics. 3 (11): 1093–101. doi:10.1074/mcp.M400085-MCP200. PMID 15345747. {{cite journal}}: Explicit use of et al. in: |author= (help)CS1 maint: multiple names: authors list (link) CS1 maint: unflagged free DOI (link)
  • Johnson AD, Kavousi M, Smith AV; et al. (2009). "Genome-wide association meta-analysis for total serum bilirubin levels". Hum. Mol. Genet. 18 (14): 2700–10. doi:10.1093/hmg/ddp202. PMID 19414484. {{cite journal}}: Explicit use of et al. in: |author= (help)CS1 maint: multiple names: authors list (link)
  • Lim J, Hao T, Shaw C; et al. (2006). "A protein-protein interaction network for human inherited ataxias and disorders of Purkinje cell degeneration". Cell. 125 (4): 801–14. doi:10.1016/j.cell.2006.03.032. PMID 16713569. {{cite journal}}: Explicit use of et al. in: |author= (help)CS1 maint: multiple names: authors list (link)
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