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'''''Pseudocnus echinatus''''', formerly known as ''Cucumaria echinata'', is a [[species]] of [[sea cucumber]] in the genus ''[[Pseudocnus]]''.
'''''Pseudocnus echinatus''''', formerly known as ''Cucumaria echinata'', is a [[species]] of [[sea cucumber]] in the genus ''[[Pseudocnus]]''.


''Pseudocnus echinatus'' is found in the [[Indo-Pacific]] from the [[Red Sea]] and [[Bay of Bengal]] to China and Japan.
''Pseudocnus echinatus'' is found in the [[Indo-Pacific]] from the [[Red Sea]] and [[Bay of Bengal]] to China and Japan. It is known to produce a [[lectin]] that has the ability to block the development of ''[[Plasmodium]]'', the causal agent of [[malaria]], when it is expressed in genetically modified ''[[Anopheles]]'' [[mosquito]]es.<ref>{{cite journal |vauthors=Yoshida S, Shimada Y, Kondoh D |title=Hemolytic C-type lectin CEL-III from sea cucumber expressed in transgenic mosquitoes impairs malaria parasite development |journal=PLoS Pathog. |volume=3 |issue=12 |pages=e192 |year=2007 |pmid=18159942 |doi=10.1371/journal.ppat.0030192 |url=http://www.plospathogens.org/article/info:doi/10.1371/journal.ppat.0030192 |pmc=2151087|display-authors=etal}}</ref>


==Biology==
==Biology==
Nearly all sea cucumbers are [[Dioecy|dioecious]], with males and females being indistinguishable externally. Spawning takes place in this species between mid-June and early August, usually in the late afternoon. The gametes are liberated into the water column and fertilisation takes place at once. The larvae are [[plankton]]ic at first before settling on the seabed, growing feeding tentacles and metamorphosing into juvenile sea cucumbers.<ref name=Khanna>{{cite book|author=Khanna, D.R.|title=Biology of Echinodermata|url=https://books.google.com/books?id=ff585KW9yFYC&pg=PA149 |year=2005 |publisher=Discovery Publishing House |isbn=978-81-7141-948-7 |page=149 }}</ref>
Nearly all sea cucumbers are [[Dioecy|dioecious]], with males and females being indistinguishable externally. Spawning takes place in this species between mid-June and early August, usually in the late afternoon. The gametes are liberated into the water column and fertilisation takes place at once. The larvae are [[plankton]]ic at first before settling on the seabed, growing feeding tentacles and [[Metamorphosis|metamorphosing]] into juvenile sea cucumbers.<ref name=Khanna>{{cite book|author=Khanna, D.R.|title=Biology of Echinodermata|url=https://books.google.com/books?id=ff585KW9yFYC&pg=PA149 |year=2005 |publisher=Discovery Publishing House |isbn=978-81-7141-948-7 |page=149 }}</ref>

==Research==
''Pseudocnus echinatus'' has been researched as a possible source of bioactive molecules and has been found to contain a [[galactose]]-specific [[lectin]] with haemolytic activity.<ref name=Matranga>{{cite book|author=Matranga, Valeria |title=Echinodermata |url=https://books.google.com/books?id=8_VzEC2DF1EC&pg=PA4 |year=2005 |publisher=Springer Science & Business Media|isbn=978-3-540-24402-8 |page=4}}</ref> This binds to the exterior of [[red blood cell]]s, damaging the cell membrane and causing [[lysis]]. This [[lectin]] has the ability to block the development of ''[[Plasmodium]]'', the causal agent of [[malaria]], when it is expressed in genetically modified ''[[Anopheles]]'' [[mosquito]]es.<ref>{{cite journal |vauthors=Yoshida S, Shimada Y, Kondoh D |title=Hemolytic C-type lectin CEL-III from sea cucumber expressed in transgenic mosquitoes impairs malaria parasite development |journal=PLoS Pathog. |volume=3 |issue=12 |pages=e192 |year=2007 |pmid=18159942 |doi=10.1371/journal.ppat.0030192 |url=http://www.plospathogens.org/article/info:doi/10.1371/journal.ppat.0030192 |pmc=2151087|display-authors=etal}}</ref>


==References==
==References==

Revision as of 20:01, 3 November 2018

Pseudocnus echinatus
Scientific classification
Kingdom:
Phylum:
Class:
Order:
Family:
Genus:
Species:
P. echinatus
Binomial name
Pseudocnus echinatus
Synonyms[1]

Cucumaria echinata

Pseudocnus echinatus, formerly known as Cucumaria echinata, is a species of sea cucumber in the genus Pseudocnus.

Pseudocnus echinatus is found in the Indo-Pacific from the Red Sea and Bay of Bengal to China and Japan.

Biology

Nearly all sea cucumbers are dioecious, with males and females being indistinguishable externally. Spawning takes place in this species between mid-June and early August, usually in the late afternoon. The gametes are liberated into the water column and fertilisation takes place at once. The larvae are planktonic at first before settling on the seabed, growing feeding tentacles and metamorphosing into juvenile sea cucumbers.[2]

Research

Pseudocnus echinatus has been researched as a possible source of bioactive molecules and has been found to contain a galactose-specific lectin with haemolytic activity.[3] This binds to the exterior of red blood cells, damaging the cell membrane and causing lysis. This lectin has the ability to block the development of Plasmodium, the causal agent of malaria, when it is expressed in genetically modified Anopheles mosquitoes.[4]

References

  1. ^ a b Paulay, Gustav (2018). "Pseudocnus echinatus (von Marenzeller, 1881)". WoRMS. World Register of Marine Species. Retrieved 3 November 2018.
  2. ^ Khanna, D.R. (2005). Biology of Echinodermata. Discovery Publishing House. p. 149. ISBN 978-81-7141-948-7.
  3. ^ Matranga, Valeria (2005). Echinodermata. Springer Science & Business Media. p. 4. ISBN 978-3-540-24402-8.
  4. ^ Yoshida S, Shimada Y, Kondoh D, et al. (2007). "Hemolytic C-type lectin CEL-III from sea cucumber expressed in transgenic mosquitoes impairs malaria parasite development". PLoS Pathog. 3 (12): e192. doi:10.1371/journal.ppat.0030192. PMC 2151087. PMID 18159942.{{cite journal}}: CS1 maint: unflagged free DOI (link)