The 1981 CONCACAF Champions' Cup was the 17th edition of the annual international club football competition held in the CONCACAF region (North America, Central America and the Caribbean), the CONCACAF Champions' Cup. It determined that year's club champion of association football in the CONCACAF region and was played from 26 April 1980 till 2 February 1981.
The teams were split in 2 zones, North/Central American and Caribbean, (as North and Central American sections combined to qualify one team for the final), each one qualifying the winner to the final tournament. All the matches in the tournament were played under the home/away match system.
SV Transvaal from Suriname won the final, and became for the second time CONCACAF champion in their history.