The 2020–21 Cypriot Cup was the 79th edition of the Cypriot Cup. A total of 26 clubs were accepted to enter the competition. It began in September 2020 with the first round and will conclude in May 2021 with the final. The winner of the Cup will qualify for the 2021–22 Europa League third qualifying round.
First round
The first round draw took place on 4 September 2020[1] and the matches were played on 16 September – 21 October 2020. The four clubs qualified for European competition, Omonia, Anorthosis Famagusta, APOEL and Apollon Limassol, received a bye for this round. Enosis Neon Paralimni received another bye in the draw.[2]
The second round draw took place on 19 October 2020[3] and the matches were played on 28 October 2020 – 20 January 2021. Omonia received a bye to the quarter-finals due to participating in the 2020–21 UEFA Europa League group stage.