|Accelerated phase chronic myelogenous leukemia
|Classification and external resources
Accelerated phase chronic myelogenous leukemia is a phase of chronic myelogenous leukemia in which the disease is progressing. In this phase, 10-19 % of the cells in the blood and bone marrow are blast cells (immature blood cells).In accelerated phase, Leukemia cells grow quickly and common symptoms include fever, bone pain, swollen spleen, etc. Prognosis is very poor once chronic myelogenous leukemia reaches the accelerated phase-it behaves similary to acute myeloid leukemia.Patients treated with imatinib, dasatinib, and nilotinib have shown meaningful rates of hematologic and cytogenetic response.