Amezinium metilsulfate

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Amezinium metilsulfate
Amezinium metilsulfate.png
Systematic (IUPAC) name
6-Methoxy-1-phenylpyridazin-1-ium-4-amine; methyl sulfate
Clinical data
AHFS/ International Drug Names
Legal status Prescription only
Routes Oral
CAS number 30578-37-1 N
ATC code C01CA25
PubChem CID 71926
ChemSpider 64937 YesY
KEGG D01304 YesY
Chemical data
Formula C12H15N3O5S 
Mol. mass 313.32 g/mol
 N (what is this?)  (verify)

Amezinium metilsulfate (INN, trade name Regulton) is a sympathomimetic drug used for the treatment of low blood pressure. It has multiple mechanisms, including stimulation of alpha and beta-1 receptors and inhibition of noradrenaline and tyramine uptake.[1][2]


  1. ^ Araújo, D; Caramona, MM; Osswald, W (1983). "On the mechanism of action of amezinium methylsulphate on the dog saphenous vein". European Journal of Pharmacology 90 (2–3): 203–14. doi:10.1016/0014-2999(83)90238-8. PMID 6873182.  edit
  2. ^ Lenke, D.; Gries, J.; Kretzschmar, R. (1981). "Pharmacology of amezinium, a novel antihypotensive drug. III. Studies on the mechanism of action". Arzneimittel-Forschung 31 (9a): 1558–1565. PMID 7197970.  edit