The Axe Murder Boyz are from Denver. They are originally from the West Denver area of the city. James and Mike Garcia are brothers of Mexican-American descent and Spanish descent. Axe Murder Boyz released a series of underground local releases on their own label, Axe Recordings, before creating Canonize Productions and releasing The Unforgiven Forest in 2004.
In 2005, AMB won the Underground Psychos contest that Psychopathic Records was holding. Following a brief tour with Insane Clown Posse, Axe Murder Boyz signed to Psychopathic Records in 2006, releasing Blood In, Blood Out. The album peaked at #11 on the Billboard Top Heatseekers chart, #22 on the Top Independent Albums chart, #199 on the Top Internet Albums chart and #199 on the Billboard 200.
In 2008, the duo released Gods Hand through Canonize and Psychopathic subsidiary Hatchet House. The album peaked at #11 on the Top Heatseekers chart, and #36 on the Top Independent Albums chart. In 2010, Bonez Dubb and Otis appeared in the Psychopathic film Big Money Rustlas and released the EP, Body In A Hole, before leaving Hatchet House. At the 2013 Gathering of the Juggalos, Violent J announced AMB's return to Psychopathic records. In an interview with yamedia.net, Otis said that The Garcia Brothers would be released before Christmas.
In the February 28, 2014 edition of the Hatchet Hetald it was announced "The Garcia Brothers" will be released on March 25, 2014. It will include guest features from Insane Clown Posse, Anybody Killa and Big Hoodoo. On March 6, 2014 the track list for The Garcia Brothers on faygoluvers.net AMB will be going on "The Family Remains Eternal Tour" in 2014 to promote The Garcia Brothers album and will be documenting footage on each tour date and will be releasing it, as was reported by faygoluvers.net. During AMB's 2014 GOTJ seminar, it was announced that they are going to release "Cutt & Stitched Vol. 2" possibly for free. Also it was announced that Otis will release a solo album on Psychopathic. Otis was featured on Psychopathic's new supergroup (The Killjoy Club - Violent J, Shaggy 2 Dope, DJ Paul, Crunchy Black & Koopsta Knicca) single off their debut album (Reindeer Games) titled "Panic Mode".