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CambridgeSoft was a cheminformatics software company based in Cambridge, Massachusetts, USA. The company was founded in 1986 by Stewart Rubenstein, then a graduate student in chemistry at Harvard University, and ended operations as an independent company in 2011. The historical main product is the molecule editor ChemDraw, often sold as part of the ChemOffice suite of programs. In 2011, CambridgeSoft was sold to PerkinElmer, a laboratory instruments company.

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