Epidural abscess

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Spinal Epidural Abscess[edit]

Spinal epidural abscess (SEA) is a collection of pus or inflammatory granulation between the dura mater and the vertebral column.[1] Currently the annual incidence rate of SEAs is estimated to be 2.5-3 per 10,000 hospital admissions. Incidence of SEA is on the rise, due to factors such as an aging population, increase in use of invasive spinal instrumentation, growing number of patients with risk factors such as diabetes and intravenous drug use.[1] SEAs are more common in posterior than anterior areas,[2] and the most common location is the thoracolumbar area, where epidural space is larger and contains more fat tissue.[3] SEAs are more common in males, and can occur in all ages, although highest prevalence is during the fifth and seventh decades of life.[1]


  1. ^ a b c Sendi, P.; Bregenzer, T.; Zimmerli, W. (3 November 2007). "Spinal epidural abscess in clinical practice". QJM 101 (1): 1–12. doi:10.1093/qjmed/hcm100. PMID 17982180. 
  2. ^ Darouiche, RO (Nov 9, 2006). "Spinal epidural abscess.". The New England journal of medicine 355 (19): 2012–20. PMID 17093252. 
  3. ^ Akalan, N; Ozgen, T (2000). "Infection as a cause of spinal cord compression: a review of 36 spinal epidural abscess cases.". Acta neurochirurgica 142 (1): 17–23. PMID 10664371.