Cauda equina syndrome

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Cauda equina syndrome
Classification and external resources

Cauda equina and filum terminale seen from behind.
ICD-10 G83.4
ICD-9 344.6
DiseasesDB 31115
eMedicine emerg/85 orthoped/39
MeSH C10.668.829.800.750.700

Cauda equina syndrome (CES) is a serious neurologic condition in which there is acute loss of function of the neurologic elements (nerve roots) of the spinal canal below the termination (conus) of the spinal cord.

Contents

[edit] Causes

After the conus, the canal contains a mass of nerves (the cauda equina or "horse-tail") that branches off the lower end of the spinal cord and contains the nerve roots from L1-5 and S1-5. The nerve roots from L4-S4 join in the sacral plexus which affects the sciatic nerve, which travels caudally (toward the feet).

[edit] Tumors and lesions

Any lesion which compresses or disturbs the function of the cauda equina may disable the nerves although the most common is a central disc prolapse.

Metastatic disease should be suspected in every patient with weight loss and cauda equina syndrome.[1]

[edit] Trauma

Also caused by direct trauma from lumbar puncture, and spinal anaesthesia involving trauma from catheters and high local anaesthetic concentrations around the cauda equina. Penetrating wounds such as knifewounds or gunshot wounds[2]

[edit] Spinal stenosis

Can be caused by spinal stenosis, which is when the diameter of the spinal canal narrows. This could be the result of a degenerative process of the spine (such as osteoarthritis) or a developmental defect which is present at birth. In the most severe cases of spondylolisthesis cauda equina syndrome can result.[2]

[edit] Inflammatory conditions

Chronic spinal inflammatory conditions such as Paget disease and ankylosing spondylitis can cause it. This is due to the spinal canal narrowing that these kind of syndromes can produce.[2]

[edit] Signs

Signs include weakness of the muscles innervated by the compressed roots (often paraplegia), sphincter weaknesses causing urinary retention and post-void residual incontinence as assessed by catheterizing after the patient has urinated. Also, there may be decreased anal tone; sexual dysfunction; saddle anesthesia; bilateral leg pain and weakness; and bilateral absence of ankle reflexes. Pain may, however, be wholly absent; the patient may complain only of lack of bladder control and of saddle-anaesthesia, and may walk into the consulting-room.

Diagnosis is usually confirmed by an MRI scan or CT scan, depending on availability. If cauda equina syndrome exists, surgery is an option depending on the etiology discovered and the patient's candidacy for major spine surgery.

[edit] Treatment/management

The management of true cauda equina syndrome frequently involves surgical decompression.

Cauda equina syndrome of sudden onset is regarded as a medical emergency. Surgical decompression by means of laminectomy or other approaches may be undertaken within 48 hours of symptoms developing if a compressive lesion, e.g. ruptured disc, epidural abscess, tumor or hematoma is demonstrated. This treatment may significantly improve the chance that long-term neurological damage will be avoided.

[edit] Prognosis

The prognosis for complete recovery is dependent upon many factors. The most important of these factors is the severity and duration of compression upon the damaged nerve(s). As a general rule the longer the interval of time before intervention to remove the compression causing nerve damage the greater the damage caused to the nerve(s).

Damage can be so severe and/or prolonged that nerve regrowth is impossible. In such cases the nerve damage will be permanent. In cases where the nerve(s) has been damaged but is still capable of regrowth, recovery time is widely variable. Quick surgical intervention can lead to complete recovery almost immediately afterwards. Delayed or severe nerve damage can mean up to several years' recovery time because nerve growth is exceptionally slow.

[edit] Prevention

Early diagnosis can allow for preventive treatment, signs that allow early diagnosis include changes in bowel and bladder function and loss of feeling in groin.[3]

[edit] References

  1. ^ Walid MS, Ajjan M, Johnston KW, Robinson JS. (2008). "Cauda Equina Syndrome--Think of Cancer". The Permanente Journal. 12 (2): 48–51. ISSN 1552-5767. 
  2. ^ a b c Jason C Eck, DO, MS. "Cauda Equina Syndrome". emedicinehealth.com. http://www.emedicinehealth.com/cauda_equina_syndrome/article_em.htm#Cauda%20Equina%20Syndrome%20Overview. Retrieved 2009-04-25. 
  3. ^ C Eck, Jason. "Cauda Equina Syndrome (cont.)". emedicinehealth.com. http://www.emedicinehealth.com/cauda_equina_syndrome/page10_em.htm#Prevention. Retrieved 2009-04-25. 

[edit] External links