Murakami originally wanted to be a comic book artist. His friend from junior high and high school, Keith Weesner, got a job working on Batman: The Animated Series as a background artist and informed Murakami when they were hiring artists at Warner Bros. Murakami was given a storyboard test, which he failed. But seeing his drawing talent, he was hired anyway.
Working closely with Bruce Timm, Murakami worked as a character designer and storyboard artist from 1991 to 1993. From 1995 to 1999, Murakami worked as Art Director on Superman: The Animated Series and The New Batman/Superman Adventures.
Murakami was promoted to producer for Batman Beyond and won an Emmy Award in 2001 for his work on the series. In addition to producing, he also was credited for story on the movie, Batman Beyond: Return of the Joker.
In addition to producing, he was also character designer on the series. Murakami approached the show with an unusual design style, setting them apart from the rest of DC Comics animated programing. The show's style was dubbed Murakanime or "Americanime".
The popular series ran for five seasons, 65 episodes, and concluded with the movie Teen Titans: Trouble in Tokyo in 2006.
Ben 10: Alien Force and Ben 10: Ultimate Alien
Following Teen Titans, Murakami teamed up with late writer Dwayne McDuffie to develop a series for Cartoon Network's Ben 10 franchise. Murakami served as Executive Producer on Ben 10: Alien Force, which ran for three seasons and 46 episodes.
Beware the Batman
Murakami illustrated the Star Wars comic Death Star Pirates - originally published in issues #16 through #20 of the Star Wars kids magazine in 1998 and later collected in Star Wars Tales Volume 2 by Dark Horse Comics.
He also drew a cover for Teen Titans Go!, and wrote and drew for stories in Batman Adventures and Batman: Mad Love and Other Stories, winning an Eisner Award for his work in the Batman Adventures Holiday Special.
- Eisner Award - Best Single Issue - 1995 - 'Batman Adventures Holiday' Special (with Paul Dini, Bruce Timm, Ronnie del Carmen, and others)
- Annie Award - Outstanding Individual Achievement for Production Design in an Animated Television Production - 1999 - Legends of the Dark Knight - 'The New Batman/Superman Adventures'
- Annie Award - Outstanding Achievement in a Daytime Animated Television Production - 2001 - 'Batman Beyond' (with Jean MacCurdy, Alan Burnett, Paul Dini, and others)
- Emmy Award - Outstanding Special Class Animated Program - 2001 - 'Batman Beyond' (with Jean MacCurdy, Alan Burnett, Paul Dini, Bruce Timm, Hilary Bader, Stan Berkowitz, Rich Fogel, Robert Goodman, Curt Geda, Butch Lukic, Dan Riba, James Tucker, Andrea Romano)
- "Glen Murakami Five Seasons", Five Seasons of Murakanime
- "The Critical Eye | Bruce Timm and Glen Murakami", Interview at The Critical Eye, September 17, 1999.
- "Glen Murakami >> Animation, Comics, Awards", Glenmurakami.com
- Sam Register @ MIP Jr: "Beware the Batman"; "Super Best Friends Forever"; "Tom & Jerry"; "DC Nation" News