The name Quagmire was chosen by a college acquaintance of MacFarlane's; the word quagmire refers to both a soft soil that yields easily (such as quicksand), and a situation that is difficult to get out of. The title of the episode "Quagmire's Quagmire" plays on the second meaning. MacFarlane came up with Quagmire's voice after listening to fast-talking radio jockeys from the 1950s era, describing the character as a "50s radio guy on coke." The "giggity" phrase was inspired by Steve Marmel's Jerry Lewis impression. Quagmire's home follows the same retro theme, decked out in a style reminiscent of the swinging party set of the 1950s and '60s; nearly every part of the house has a discreetly hidden bed.
Quagmire is a bachelor who works as a commercial airline pilot. He lives on Spooner Street where he is a neighbor and friend of Peter Griffin, Cleveland Brown and Joe Swanson. He has had two spouses: Joan, a maid for the Griffins who died; and Charmise, a prostitute whom he divorced. In the episode "Quagmire's Baby", he discovers his daughter Anna Lee but puts her up for adoption; several episodes imply that Quagmire has other children due to his promiscuity.
^Miller, Shaun (2007). "Quagmire: Virtue and Perversity". In Wisnewski, J. Jeremy. Family Guy and Philosophy: A Cure for the Petarded. The Blackwell Philosophy and Pop Culture Series. Malden, MA: Blackwell Publishing. pp. 27–35. ISBN140516316X.