"Grew Up a Screw Up" is the second single from Ludacris' Release Therapy. The song features Young Jeezy, who Ludacris was previously thought to have beef with and a sample of the late The Notorious B.I.G. who sings the hook "I grew up a fucking screw up." Curiously, in the video, Young Jeezy raps a verse different from the one which appeared on the Release Therapy Disc. The video premiered on BET's 106 & Park as a New Joint on Friday October 13, 2006. The video has already been released on MTV Jams. The video features Slick Pulla and Bloodraw (from CTE).
The music video's concept is not as complex as other videos featuring Ludacris. It is shot outdoors, where Ludacris and Young Jeezy rap. Behind them is a screen that shows videos and pictures of the places where they grew up. It was directed by Chaka Zulu and premiered on BET's 106 & Park on October 13, 2006.