Guillermo Subiabre Astorga (born 25 February 1903 in Osorno, Chile; died in 1964) was a Chilean footballer. During his career he played for Colo-Colo (1927–1934), Santiago Wanderers, and the Chile national football team. He also participated in the 1928 Summer Olympics and in the 1930 FIFA World Cup.
At Colo-Colo, Subiabre played as a striker for eight seasons, six of which were part of the amateur period and two of which were part of the professional period. In 1934, he was recognized as a lifetime honorary player for Colo-Colo.