Haemangiopericytoma, Gomori methenamine silver stain
|Classification and external resources|
|ICD-10||C49 (ILDS C49.M20)|
A hemangiopericytoma (HPC) is a type of soft tissue sarcoma that originates in the pericytes in the walls of capillaries. When inside the nervous system, although not strictly a meningioma tumor, it is a meningeal tumor with a special aggressive behavior. It was first characterized in 1942.
Hemangiopericytoma located in the cerebral cavity is an aggressive tumor of the Mesenchyme with oval nuclei with scant cytoplasm. "There is dense intercellular reticulin staining. Tumor cells can be fibroblastic, myxoid, or pericytic. These tumors, in contrast to meningiomas, do not stain with epithelial membrane antigen. They have a grade 2 or 3 biological behavior, and need to be distinguished from benign meningiomas because of their high rate of recurrence (68.2%) and metastases (Maier et al 1992; Kleihues et al 1993 )." 
The word hemangiopericytoma comes from the ancient Greek words: haema (combining form of Ancient Greek αἷμα, haîma, “blood”), angio- (means blood vessel), angioma, peri- (prefix meaning “about” or “around”, “enclosing” or “surrounding”, and “near”, appearing in loanwords from Greek; and -cytoma (refers to the cells surrounding the blood vessel walls).
- Stout AP, Murray MR(1942) Hemangiopericytoma: a vascular tumor featuring Zimmermann's pericytes. Ann Surg 116, 26-33
- Maier H, Ofner D, Hittmair A, Kitz K, Budka H. (1992). "Classic, atypical, and anaplastic meningioma: three histopathological subtypes of clinical relevance.". Neurosurg (77): 616–23.
- Kleihues P, Burger PC, Scheithauer BW. (1993). "Histological typing of tumours of the central nervous system. 2nd ed.". World Health Organization. Berlin : Springer-Verlag (30).
- Sherman Sojka W MD, Raizer J MD, Dropcho E.J.MD. "Meningiomas". Medmerits: 2.
- Yahyazadeh, Seyed Hossein; Malekpour, Nasser; Mousavi, Mehdi; Molanayi, Saadat; Salmanian, Bahram; Mohamadi, Amin (2013). "Malignant Retroperitoneal Hemangiopericytoma: Report of a 73 Years Old Woman and Review of Literature". Thrita 2 (2): 80–83. doi:10.5812/thrita.10606. ISSN 2352-0620. Retrieved 2014-11-15.
- Ozaki N, Mukohara N, Yoshida M, Shida T (April 2006). "Successful resection of giant hemangeopericytoma originating from the left atrium". Interact Cardiovasc Thorac Surg 5 (2): 79–80. doi:10.1510/icvts.2005.124107. PMID 17670519.
- Photo of tissue
- Children's Hospital Boston
- MedPix Images of HPC
- Videos and Case Studies of Hemangioperyctoma of the Sinuses - an Educational Resource