Hesperetin

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Hesperetin
Hesperetin
Identifiers
CAS number 520-33-2 YesY
PubChem 72281
ChemSpider 65234 YesY
UNII Q9Q3D557F1 YesY
EC number 208-290-2
DrugBank DB01094
KEGG C01709 YesY
ChEBI CHEBI:28230 YesY
ChEMBL CHEMBL399121 YesY
Jmol-3D images Image 1
Properties
Molecular formula C16H14O6
Molar mass 302.28 g mol−1
Melting point 226–228 °C (439–442 °F; 499–501 K)
Solubility in other solvents Sol. EtOH, alkalis
Except where noted otherwise, data are given for materials in their standard state (at 25 °C (77 °F), 100 kPa)
 YesY (verify) (what is: YesY/N?)
Infobox references

Hesperetin is a bioflavonoid and, to be more specific, a flavanone.

Glycosides[edit]

A variety of glycosides of hesperetin are known, including:

  • Hesperidin (hesperetin 7-rutinoside) is a water-insoluble flavonoid glycoside whose solubility is below 5 μg/ml in water.[1] Hesperidin is found in citrus fruits and upon ingestion it releases its aglycone, hesperetin.

Metabolism[edit]

Hesperidin 6-O-α-L-rhamnosyl-β-D-glucosidase is an enzyme that uses hesperidin and H2O to produce hesperetin and rutinose. It is found in the hyphomycetes species Stilbella fimetaria.

References[edit]

  1. ^ Majumdar S.; Srirangam, R. (2009). "Solubility, stability, physicochemical characteristics and in vitro ocular tissue permeability of hesperidin: a natural bioflavonoid". Pharm Res. 26: 1217–1225. 
  2. ^ J.S. Chauhan, S.K. Srivastava and M. Sultan, Phytochemistry (1978). Hesperetin 7-rhamnoside from Cordia oblique 17 (2). p. 334. doi:10.1016/S0031-9422(00)94187-6.