Luis Garisto (el loco) began his professional career in 1960 with Uruguayn club Defensor, known today as Defensor Sporting, he was transferred to Club Independiente of Argentina in Buenos Aires. He played there for several years, participating in all 5 consequtive championships with his club, 3 Libertadores cups, and 2 world club championships. Subsequently he was transfer to Penarol of Montevideo Uruguay, as a Captain of this squad they obtained 2 championships. Then went to Club Cobreloa in Chile. With this club he gained the B and A division consequtively and other several international cups such as Libertadores de America Cup and the Intercontinental Cup. In 1973 he signed with the Chilean club Cobreloa and played for the Uruguayan Squad in the World Cup in Germany in 1974.
In 1974, Garisto punched Australian international Ray Baartz in the throat and jaw during a friendly fixture at the Sydney Cricket Ground, prematurely ending Baartz's playing career.