Merton F. Utter

Merton Franklin Utter
Merton Franklin Utter
Born	23 March 1917; Westboro, Missouri, USA
Died	28 November 1980 (aged 63)
Nationality	American
Alma mater	Simpson College; Iowa State College
Known for	Gluconeogenesis; Pyruvate carboxylase
Spouse	Marjorie Manifold (m. 1939)
Children	Douglas
Awards	Paul-Lewis Award in Enzyme Chemistry (1956); American Academy of Arts and Sciences (1972); National Academy of Sciences (1973)
	Scientific career
Fields	Biochemistry
Institutions	University of Minnesota; Western Reserve University; Case Western Reserve University

Merton Franklin Utter (born 23 March 1917 in Westboro, Missouri; died 28 November 1980) was an American microbiologist and biochemist.

Early life and education

In his first year the family moved to New Market, Iowa, for his father's job in a bank. His mother worked as an organist in churches, which stimulated Utter's lifelong love of music. His education began in New Market. The family later moved to Coin, Iowa where In 1934 he graduated from high school. He attended Simpson College in Indianola, Iowa, where he graduated in 1938. Merton went to graduate school until 1942 at Iowa State College, where his advisor was Chester Hamlin Werkman. In 1939 he married Marjorie Manifold, who worked as a secretary for Theodore Schultz.

Academic career

In 1944 Utter was appointed assistant professor at the University of Minnesota; in 1946 he became an associate professor at Western Reserve University in Cleveland. His son Douglas Max Utter was born in 1950, and became an expressionist artist. Utter was appointed full professor in 1956. Between 1965 and 1976, he was also chair of the department of biochemistry. During his time at Western Reserve (later Case Western Reserve University), he spent three years at other universities: in 1953 with the help of the Fulbright Program at the University of South Australia, in 1960 at the University of Oxford, and in 1968 at the University of Leicester, where he met Hans Kornberg daily for discussion on the way to work. He served as associate editor of the Journal of Biological Chemistry. He became a member of the American Academy of Arts and Sciences in 1972 and In 1973 was honored with membership in the National Academy of Sciences.

Scientific contributions

Utter was a pioneer in the fields of bacterial and intermediary metabolism. One of his key findings was that gluconeogenesis is not reverse glycolysis. In 1966 he examined the quaternary structure of pyruvate carboxylase of chickens by means of electron microscopy, which was one of its first applications for this purpose. The enzyme was found to be a tetramer, which was later found to be true for other organisms by researchers like Gerhard Gottschalk. Late in his career, he made contributions to the study of Leigh disease.

References

Wood, H. G.; Hanson, R. W. (1987), Merton Franklin Utter, 1917—1980 (PDF), Biographical Memoirs, vol. 56, Washington, DC: National Academy of Sciences, pp. 475–499, doi:10.17226/897