Reticulocytopenia

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Reticulocytopenia
Classification and external resources
ICD-9 282.62
DiseasesDB 10703

Reticulocytopenia, or "aplastic crisis", is the medical term for an abnormal decrease of reticulocytes in the body. Reticulocytes are immature red blood cells. Reticulocytopenia may be a result of viral Parvovirus B19 infection, which invades and destroys red blood cell precursors and halts the red cell production. If infection occurs in individuals with sickle cell anemia[1] or spherocytosis, that will lead to incorporation of 2 anemia-induced mechanisms: decrease red cell production and hemolysis. The result is a severe anemia (aplastic crisis) which may require blood transfusion.

References[edit]

  1. ^ "Sickle Cell Disease - Basic Principles and Clinical Practice" Edited by Stephen H. Embury, Robert P. Hebbel, Narla Mohandas and Martin Steinberg. Copyright 1996 by Lippincott-Raven. Section IV p352.