Royal Chapel of Granada
- Doña Isabel de Castilla I, Queen Isabella I (1451–1504)
- Don Fernando de Aragón II, King Ferdinand II (1452–1516)
- Their daughter Queen Juana I of Castile, León, and Aragon (Joanna I, Spanish: Juana la Loca) (1479-1555)
- Her husband Felipe I (Philip I, Philip the Handsome, Spanish: Felipe El Hermoso) (1478-1506)
- Their oldest grandson Miguel da Paz, Prince of Asturias, Portugal and Girona (Spanish: Infante Miguel) (1498–1500).
There are relics, portraits, tapestries, ornaments, Baroque sculptures and paintings on display in the Sacristy Museum. The works are predominantly by Flemish, Italian and Spanish painters of the 15th Century, including pieces by Rogier van der Weyden, Dirk Bouts, Hans Memling, Botticelli, Perugino and Bartolomé Bermejo.
The Nasrid dynasty of Granada was the last Moorish dominion of Al-Andalus to fall in the Reconquista (Reconquest). It occurred in 1492 during the reign of the Catholic Monarchs, with the city an important step in their successful reign. On September 13, 1504, they decided they wanted their remains to be taken to Granada, and for this purpose a Royal Warrant was issued at Medina del Campo, Castile-León, for a Royal Chapel to be built. It was constructed between 1505 and 1517 in the Gothic style and dedicated to St. John the Baptist and St. John the Evangelist. Queen Isabella's, King Ferdinand's, Infante Miguel's, and Philip I's remains were not taken there until 1521.
Notable maestros de capilla at the Royal Chapel included:
- Bernardino de Figueroa - later bishop at Brindisi in Italy 1571-1591.
- Rodrigo de Ceballos (1561–1581)
- Ambrosio Cotes (1581–1596)
- Spanish Monarchs since Charles V have been buried in the crypt at the Escorial in Castile.
- Prior to Isabel I, royal families were buried in diverse cities in the Iberian peninsula.