Saccharomyces Genome Database

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Saccharomyces Genome Database (SGD)
Developer(s) J Michael Cherry, Rama Balakrishnan, Gail Binkley, Maria Costanzo, Stacia Engel, Ben Hitz, Eurie Hong, Rob Nash, Rey Andrada, Stuart Miyasato, Edith Wong, Shuai Weng
Operating system Unix, Mac, MS-Windows
Type Bioinformatics tool, Model Organism Database
Licence Free
Website http://www.yeastgenome.org

The Saccharomyces Genome Database is a scientific database of the molecular biology and genetics of the yeast Saccharomyces cerevisiae, which is commonly known as baker's or budding yeast.[1]

The Saccharomyces Genome Database (SGD) provides Internet access to the complete Saccharomyces cerevisiae reference genome DNA sequence, its genes and their products, the phenotypes of its mutants, and the literature supporting these data. The amount of information and the number of features provided by SGD have increased greatly following the release of the S. cerevisiae genomic sequence. SGD aids researchers by providing not only basic information, but also tools such as sequence similarity searching that lead to detailed information about features of the genome and relationships between genes. SGD presents information using a variety of user-friendly, dynamically created graphical displays illustrating physical, genetic and sequence feature maps.

The biocurators at SGD aim to annotate each gene by identifying function(s) from primary literature and linking to terms using the structured knowledge representation in the Gene Ontology.[2] Additionally, functions identified from high throughput experiments as well as computationally predicted function annotations are included from GO Annotation project.[3]

References[edit]

  1. ^ Cherry JM, Ball C, Weng S, Juvik G, Schmidt R, Adler C, Dunn B, Dwight S, Riles L, Mortimer RK, Botstein D (May 1997). "Genetic and physical maps of Saccharomyces cerevisiae". Nature 387 (6632 Suppl): 67–73. PMC 3057085. PMID 9169866. 
  2. ^ Dwight SS, Harris MA, Dolinski K et al. (January 2002). "Saccharomyces Genome Database (SGD) provides secondary gene annotation using the Gene Ontology (GO)". Nucleic Acids Res. 30 (1): 69–72. doi:10.1093/nar/30.1.69. PMC 99086. PMID 11752257. 
  3. ^ Hong EL, Balakrishnan R, Dong Q et al. (January 2008). "Gene Ontology annotations at SGD: new data sources and annotation methods". Nucleic Acids Res. 36 (Database issue): D577–81. doi:10.1093/nar/gkm909. PMC 2238894. PMID 17982175. 

External links[edit]