The Skopje Statistical Region is one of eight statistical regions of the Republic of Macedonia. Skopje, located in northern Macedonia, borders Serbia to the north. Internally, it borders the Vardar, Polog, Northeastern, Eastern, and Southwestern statistical regions.
The region consists of the City of Skopje and the following municipalities:
The current population of the Skopje Statistical Region is 578,144 citizens, according to the last population census in 2002, accounting for 28.6% of the total national population. The region is the largest by population in Macedonia.