Talk:Viral hemorrhagic fever
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The current outbreak of Dengue in Brazil as reported by BBC news ( http://news.bbc.co.uk/1/hi/world/americas/7322654.stm) could probably do with a metion in this section —Preceding unsigned comment added by 188.8.131.52 (talk) 15:50, 2 April 2008 (UTC)
The article on viral hemorrhagic fever (VHF) states that the disease is caused by members of four RNA virus families: Arena-, Filo-, Bunya-, and Flaviviridae. In fact, VHF is caused by members of FIVE RNA virus families; infection by members of the Alphaviridae family can also cause VHF, although it is somewhat unusual. Chikungunya virus (CHIK) is an example of an Alphavirus associated with VHF during the most extreme and severe cases. In addition, it is likely that the incidence of Alphavirus associated VHF is grossly underestimated, largely due to frequent misdiagnosis. CHIK, for example, is often diagnosed as Dengue - a VHF-associated member of the Flaviviridae family.
Part of my MS thesis deals with VHF caused by the alphavirus Sindbis (SB) in a mouse model of infection. Details of my research can be found in the following research paper:
Non-pathogenic Sindbis virus causes hemorrhagic fever in the absence of alpha/beta and gamma interferons. Ryman KD, Meier KC, Gardner CL, Adegboyega PA, Klimstra WB. Virology. 2007 Nov 25;368 (2):273-85. Epub 2007 Aug 2.
My own mistake...
Don't I feel an idiot?! Copying and pasting leads to yet another mistake... the family is Togaviridae... not alphviridae... genus is alphavirus... started out with genus... changed to family, but without checking carefully... managed to fuse the two words - way to go me! always proofread! —Preceding unsigned comment added by 184.108.40.206 (talk) 22:54, 2 April 2008 (UTC)
The link to Togaviridae lists encephalitis as the resulting disease of this family. Why go against all other published facts on VHF by saying it is caused by 5 families just beacuse one person claims their masters thesis included a Togaviridae that rarely causes VHF? Maybe it is just a VHF-like illness. This disease eassily spreads. Stay away from any one who has it. 220.127.116.11 (talk) 18:14, 13 April 2010 (UTC)