|Brain: Wernicke's area|
|Approximate location of Wernicke's area highlighted in grey|
Wernicke's area (// or //; German: [ˈvɛʁnɪkə]) is one of the two parts of the cerebral cortex linked since the late nineteenth century to speech (the other is Broca's area). It is involved in the understanding of written and spoken language. It is traditionally considered to consist of the posterior section of the superior temporal gyrus (STG) in the dominant cerebral hemisphere (which is the left hemisphere in about 97% of people).
Wernicke and aphasia 
Wernicke's area is named after Carl Wernicke, a German neurologist and psychiatrist who, in 1874, hypothesized a link between the left posterior section of the superior temporal gyrus and the reflexive mimicking of words and their syllables that associated the sensory and motor images of spoken words. He did this on the basis of the location of brain injuries that caused aphasia. Receptive aphasia in which such abilities are preserved is also known as Wernicke's aphasia. In this condition there is a major impairment of language comprehension, while speech retains a natural-sounding rhythm and a relatively normal syntax. Language as a result is largely meaningless (a condition sometimes called fluent or jargon aphasia).
While neuroimaging and lesion evidence generally support the idea that malfunction of or damage to Wernicke's area is common in people with receptive aphasia, this is not always so. Some people may use the right hemisphere for language, and isolated damage of Wernicke's area cortex (sparing white matter and other areas) may not cause severe receptive aphasia. Even when patients with Wernicke's area lesions have comprehension deficits, these are usually not restricted to language processing alone. For example, one study found that patients with posterior lesions also had trouble understanding nonverbal sounds like animal and machine noises. In fact, for Wernicke's area, the impairments in nonverbal sounds were statistically stronger than for verbal sounds.
Right homologous area 
Research using Transcranial magnetic stimulation suggests that the area corresponding to the Wernicke’s area in the non-dominant cerebral hemisphere has a role in processing and resolution of subordinate meanings of ambiguous words—such as (‘‘river’’) when given the ambiguous word (‘‘bank’’). In contrast, the Wernicke's area in the dominant hemisphere processes dominant word meanings (‘‘teller’’ given ‘‘bank’’).
Modern views 
|“||There are some suggestions that middle and inferior temporal gyri and basal temporal cortex reflect lexical processing ... there is consensus that the STG from rostral to caudal fields and the STS constitute the neural tissue in which many of the critical computations for speech recognition are executed ... aspects of Broca’s area (Brodmann areas 44 and 45) are also regularly implicated in speech processing.
... the range of areas implicated in speech processing go well beyond the classical language areas typically mentioned for speech; the vast majority of textbooks still state that this aspect of perception and language processing occurs in Wernicke’s area (the posterior third of the STG).
Support for a broad range of speech processing areas was furthered by a recent study done at University of Rochester in which American Sign Language native speakers were subject to MRIs while interpreting sentences that identified a relationship using either syntax (relationship is determined by the word order) or inflection (relationship is determined by physical motion of "moving hands through space or signing on one side of the body"). Distinct areas of the brain were activated with the frontal cortex (associated with ability to put information into sequences) being more active in the syntax condition and the temporal lobes (associated with dividing information into its constituent parts) being more active in the inflection condition. However, these areas are not mutually exclusive and show a large amount of overlap. These findings imply that while speech processing is a very complex process, the brain may be using fairly basic, preexisting computational methods.
- Wernicke K. (1995). "The aphasia symptom-complex: A psychological study on an anatomical basis (1875)". In Paul Eling. Reader in the History of Aphasia: From sasi(Franz Gall to) 4. Amsterdam: John Benjamins Pub Co. pp. 69–89. ISBN 90-272-1893-5.
- Bogen JE, Bogen GM (1976). "Wernicke's region—Where is it?". Ann. N. Y. Acad. Sci. 280: 834–43. doi:10.1111/j.1749-6632.1976.tb25546.x. PMID 1070943.
- Dronkers NF., Redfern B B., Knight R T. (2000). "The neural architecture of language disorders". In Bizzi, Emilio; Gazzaniga, Michael S. The New cognitive neurosciences (2nd ed.). Cambridge, Mass: MIT Press. pp. 949–58. ISBN 0-262-07195-9.
- Saygin, AP; Dick, F; Wilson, SM; Dronkers, NF; Bates, E (2003). "Neural resources for processing language and environmental sounds: evidence from aphasia". Brain : a journal of neurology 126 (Pt 4): 928–45. PMID 12615649.
- Harpaz Y, Levkovitz Y, Lavidor M (October 2009). "Lexical ambiguity resolution in Wernicke's area and its right homologue". Cortex 45 (9): 1097–103. doi:10.1016/j.cortex.2009.01.002. PMID 19251255.
- Poeppel D, Idsardi WJ, van Wassenhove V (March 2008). "Speech perception at the interface of neurobiology and linguistics". Philos. Trans. R. Soc. Lond., B, Biol. Sci. 363 (1493): 1071–86. doi:10.1098/rstb.2007.2160. PMC 2606797. PMID 17890189.
- Newman AJ, Supalla T, Hauser P, Newport EL, Bravelier D (2010). "Dissociating neural subsystems for grammar by contrasting word order and inflection". Proceedings of the National Academy of Sciences, 16 (107): 7539. doi:10.1073/pnas.1003174107.
See also 
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