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Revision as of 08:25, 6 August 2011

Haemodialysis-associated amyloidosis
SpecialtyImmunology Edit this on Wikidata

Haemodialysis-associated amyloidosis is a form of amyloidosis associated with chronic renal failure.[1]

Presentation

Long-term haemodialysis results in a gradual accumulation of β2 microglobulin, a serum protein, in the blood.[2] It accumulates because it is unable to cross the dialysis filter.

Prevention

Low copper dialysis is theorized to prevent or delay onset.[3]

See also

References

  1. ^ Miyata T, Oda O, Inagi R; et al. (1993). "beta 2-Microglobulin modified with advanced glycation end products is a major component of hemodialysis-associated amyloidosis". J. Clin. Invest. 92 (3): 1243–52. doi:10.1172/JCI116696. PMC 288264. PMID 8376584. {{cite journal}}: Explicit use of et al. in: |author= (help); Unknown parameter |month= ignored (help)CS1 maint: multiple names: authors list (link)
  2. ^ Rapini, Ronald P.; Bolognia, Jean L.; Jorizzo, Joseph L. (2007). Dermatology: 2-Volume Set. St. Louis: Mosby. ISBN 1-4160-2999-0.{{cite book}}: CS1 maint: multiple names: authors list (link)
  3. ^ "BU Amyloid Treatment & Research Program".